A0A8H4JRP1 · A0A8H4JRP1_9HYPO
- ProteinTranslation factor GUF1 mitochondrial
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1988 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
Catalytic activity
- GTP + H2O = GDP + phosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 1398-1405 | GTP (UniProtKB | ChEBI) | |||
Binding site | 1463-1467 | GTP (UniProtKB | ChEBI) | |||
Binding site | 1517-1520 | GTP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial inner membrane | |
Cellular Component | mitochondrial matrix | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | mitochondrial ribosome binding | |
Biological Process | positive regulation of translation | |
Biological Process | translation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Sordariomycetes > Hypocreomycetidae > Hypocreales > Nectriaceae > Fusarium > Fusarium fujikuroi species complex
Accessions
- Primary accessionA0A8H4JRP1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Mitochondrion inner membrane ; Peripheral membrane protein
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for compositional bias, region, coiled coil, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-15 | Polar residues | |||
Region | 1-151 | Disordered | |||
Compositional bias | 52-66 | Polar residues | |||
Compositional bias | 75-89 | Polar residues | |||
Compositional bias | 123-151 | Polar residues | |||
Compositional bias | 176-203 | Polar residues | |||
Region | 176-229 | Disordered | |||
Region | 266-362 | Disordered | |||
Compositional bias | 277-315 | Polar residues | |||
Region | 426-570 | Disordered | |||
Compositional bias | 478-492 | Polar residues | |||
Compositional bias | 508-532 | Polar residues | |||
Compositional bias | 544-558 | Pro residues | |||
Coiled coil | 683-710 | ||||
Region | 751-842 | Disordered | |||
Compositional bias | 764-798 | Polar residues | |||
Compositional bias | 818-842 | Polar residues | |||
Region | 860-984 | Disordered | |||
Compositional bias | 883-912 | Polar residues | |||
Compositional bias | 930-975 | Polar residues | |||
Domain | 1389-1570 | Tr-type G | |||
Sequence similarities
Belongs to the GTP-binding elongation factor family. LepA subfamily.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,988
- Mass (Da)218,832
- Last updated2022-01-19 v1
- Checksum62AA3BD2F7FE91AF
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-15 | Polar residues | |||
Compositional bias | 52-66 | Polar residues | |||
Compositional bias | 75-89 | Polar residues | |||
Compositional bias | 123-151 | Polar residues | |||
Compositional bias | 176-203 | Polar residues | |||
Compositional bias | 277-315 | Polar residues | |||
Compositional bias | 478-492 | Polar residues | |||
Compositional bias | 508-532 | Polar residues | |||
Compositional bias | 544-558 | Pro residues | |||
Compositional bias | 764-798 | Polar residues | |||
Compositional bias | 818-842 | Polar residues | |||
Compositional bias | 883-912 | Polar residues | |||
Compositional bias | 930-975 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAADJF010000153 EMBL· GenBank· DDBJ | KAF4436354.1 EMBL· GenBank· DDBJ | Genomic DNA |