A0A8F4TK10 · A0A8F4TK10_DROBP

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processmitochondrial electron transport, NADH to ubiquinone

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 2
  • EC number

Gene names

    • Name
      ND2

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    A0A8F4TK10

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-28Helical
Transmembrane60-80Helical
Transmembrane92-114Helical
Transmembrane149-167Helical
Transmembrane198-218Helical
Transmembrane238-260Helical
Transmembrane272-297Helical
Transmembrane318-340Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-284NADH:quinone oxidoreductase/Mrp antiporter membrane subunit
Domain286-337NADH dehydrogenase subunit 2 C-terminal

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    341
  • Mass (Da)
    39,562
  • Last updated
    2022-01-19 v1
  • Checksum
    CF62A18CAF0D75D8
MFNNSSKILFITIMIIGTLITVTSNSWLGAWMGLEINLLSFIPLLSDNNNLTSTESSLKYFLTQALASTVLLFSVILLMLKNNFNNEINESFTSMIIMSSLLLKSGAAPFHFWFPNMMEGLNWMNSLLLMTWQKIAPLMLISYLNIKDLLLISVILSVIVGAIGGLNQTSLRKLMAFSSINHLGWMLSSLMISESIWLVYFLFYSFLSFILTFMFNIFKLFHLNQLFSWFVNSKILKFTLFMNFLSLGGLPPFLGFLPKWLVIQQLTSCNQYFLLTVMMMSTLVTLFFYLRICYSAFMLNYFENNWMMTLNMKNFNMNLYLILTFFSIFGLFLISLFFFML

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MK659811
EMBL· GenBank· DDBJ
QXG19139.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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