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A0A8F3FHZ7 · A0A8F3FHZ7_9CUCU

  • Protein
    NADH-ubiquinone oxidoreductase chain 2
  • Gene
    nad2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processmitochondrial electron transport, NADH to ubiquinone

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 2
  • EC number

Gene names

    • Name
      nad2

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Coleoptera > Polyphaga > Cucujiformia > Tenebrionidae > Pimeliinae > Pelecyphorus

Accessions

  • Primary accession
    A0A8F3FHZ7

Subcellular Location

Mitochondrion inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-26Helical
Transmembrane58-78Helical
Transmembrane90-112Helical
Transmembrane148-168Helical
Transmembrane196-216Helical
Transmembrane237-260Helical
Transmembrane272-293Helical
Transmembrane314-333Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-282NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 2 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    336
  • Mass (Da)
    38,888
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    57C9FE12AC78525671BC9BB8C6F31B90
MKLYKMIFFNTMIMGTLIAISAYSWMSMWMGLEINLLSVIPLFSDKKNVFSSESSLKYFITQAIASAVLLMSVIMMLLTNEFIAPTVNFYLMMVLNSALLTKLGAAPFHYWFPEVMEGLNWMNCLILLTWQKIAPMMLLMNNLMNTKFTIAIILMCMVVSTLMAFNQISLRKILTFSSINHIGWMMSTTLISFPSWLIYFLIYSILNINIIAMFNYTKSFYLNQINNIINKNKILKFSMLINFLSLGGLPPFLGFLPKWLVINWMIMNNLPLTALFMTILTLLMLYIYVRITLSSLLLHSSEPKFLNLKFSNHLLLILNFISLFSLIICTLMFNLM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MZ342780
EMBL· GenBank· DDBJ
QWZ46362.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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