A0A8F0ZVJ8 · A0A8F0ZVJ8_9BETC

Function

function

Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentribonucleoprotein complex
Cellular Componentviral nucleocapsid
Molecular FunctionRNA binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoprotein

Gene names

    • Name
      N

Organism names

  • Taxonomic identifier
  • Strain
    • Bat/Yunnan/RsYN04/2020
  • Taxonomic lineage
    Viruses > Riboviria > Orthornavirae > Pisuviricota > Pisoniviricetes > Nidovirales > Cornidovirineae > Coronaviridae > Orthocoronavirinae > Betacoronavirus > Sarbecovirus

Accessions

  • Primary accession
    A0A8F0ZVJ8

Proteomes

Subcellular Location

Virion
Note: Located inside the virion, complexed with the viral RNA. Probably associates with ER-derived membranes where it participates in viral RNA synthesis and virus budding.

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue396Phosphoserine; by host

Keywords

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-45Disordered
Domain41-168CoV N NTD
Region162-206Disordered
Compositional bias172-205Polar residues
Compositional bias227-242Polar residues
Region227-257Disordered
Domain240-357CoV N CTD
Compositional bias355-374Basic and acidic residues
Region355-410Disordered
Compositional bias395-410Polar residues

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    410
  • Mass (Da)
    44,709
  • Last updated
    2024-05-29 v1
  • Checksum
    1D5ECDAB4B800892
MSDNGPRITFGAPAGSADNNQNGERSGTRPKQRRPQGPPNNNASWFTALTQHGKEDLKFPRGQGVPINTNSGPDDQIGYYRRATRRIRGGDGKMKELSPRWYFYYLGTGPEAQLTYGTQKDGIVWVAQEGALATPKTAIGTRNPNNNAAIVLQLPQGTTLPKGFYAEGSRGGSAASSRSSSRSRGNSRNSTPGSSRGNSPARQISAGGGDTALAILLLDRLNQLESKVSGKQPSQPQTVTKKSAAEAAKKPRQKRTATKQYNVTQAFGRRGPEQTQGNFGDQELIRLGTDYKQWPQIAQFAPSASAFFGMSRIGMEVTPQGTWLTYHGAIKLDDKDPQFKDNVILLNKHIDAYKTFPPTESKKDKKKQAEDQPQPQRQKKQPTVTLLPAADLDDFSRQLQQSMNGDSTSA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias172-205Polar residues
Compositional bias227-242Polar residues
Compositional bias355-374Basic and acidic residues
Compositional bias395-410Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MZ081380
EMBL· GenBank· DDBJ
QWN56250.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

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