A0A8E6RTE1 · A0A8E6RTE1_SALET
- ProteinLipid A acyltransferase PagP
- GenepagP
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids190 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
Catalytic activity
- a 1,2-diacyl-sn-glycero-3-phosphocholine + a lipid A = a 2-acyl-sn-glycero-3-phosphocholine + a hepta-acyl lipid A
Features
Showing features for active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 62 | |||||
Sequence: H | ||||||
Site | 71 | Role in lipopolysaccharide recognition | ||||
Sequence: K | ||||||
Active site | 105 | |||||
Sequence: D | ||||||
Active site | 106 | |||||
Sequence: S | ||||||
Site | 176 | Role in the phospholipid gating | ||||
Sequence: Y |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cell outer membrane | |
Molecular Function | acyltransferase activity | |
Biological Process | lipid A biosynthetic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLipid A acyltransferase PagP
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionA0A8E6RTE1
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-29 | |||||
Sequence: MYVVMIIRKHFFIIALLVMPWLAIPPVSA | ||||||
Chain | PRO_5035016477 | 30-190 | Lipid A acyltransferase PagP | |||
Sequence: ADKGWFNTFTDNVAETWRQPEHYDLYVPAITWHARFAYDKEKTDRYNERPWGVGFGQSRWDDKGNWHGLYMMAFKDSFNKWEPIGGYGWEKTWRPLEDDNFRLGLGFTAGVTARDNWNYIPIPVLLPLASIGYGPATFQMTYIPGSYNNGNVYFAWMRFQF |
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length190
- Mass (Da)22,361
- Last updated2022-01-19 v1
- ChecksumCB5FFE15AC065CF5