A0A8D5U116 · A0A8D5U116_9CREN

Function

function

Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site25Mg2+ (UniProtKB | ChEBI)
Binding site53Mg2+ (UniProtKB | ChEBI)
Binding site171-177sn-glycerol 1-phosphate (UniProtKB | ChEBI)
Binding site203-204sn-glycerol 1-phosphate (UniProtKB | ChEBI)
Binding site225-226sn-glycerol 1-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmagnesium ion binding
Molecular Functionphosphoglycerol geranylgeranyltransferase activity
Molecular Functionpolyprenyltransferase activity
Biological Processglycerophospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Geranylgeranylglyceryl phosphate synthase
  • EC number
  • Short names
    GGGP synthase
    ; GGGPS
  • Alternative names
    • (S)-3-O-geranylgeranylglyceryl phosphate synthase
    • Phosphoglycerol geranylgeranyltransferase

Gene names

    • ORF names
      HS7_07230

Organism names

Accessions

  • Primary accession
    A0A8D5U116

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the GGGP/HepGP synthase family. Group II subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    27,051
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    933F73BADAFC81881AC79529D0B798EA
MKGKVEKYLEKLRSEGESIHFSLIDPEKLPHDLEKVAKQLYNSGTSAFLVGGTLGVTHEIFQYVLDVLGDFDIPKIIFPSNTNLVDSKADAILFMSLLNSDDLYFVVGAQVYSSLMVKKLGLEALPTAYLIIGNGGTASHIGKARPIPFDNYVLASAYASAAELLGMRYIYLEAGSGSPETVRPEMIKSIKSVVPNAYLIVGGGIRSEDKAISVTEAGADIIVTGNLIEENIDKAVSIIERIRKVKKRV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP024596
EMBL· GenBank· DDBJ
BCU67286.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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