A0A8D5U116 · A0A8D5U116_9CREN
- ProteinGeranylgeranylglyceryl phosphate synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids249 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
Catalytic activity
- sn-glycerol 1-phosphate + (2E,6E,10E)-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate
Cofactor
Pathway
Membrane lipid metabolism; glycerophospholipid metabolism.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 25 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 53 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 171-177 | sn-glycerol 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 203-204 | sn-glycerol 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 225-226 | sn-glycerol 1-phosphate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | magnesium ion binding | |
Molecular Function | phosphoglycerol geranylgeranyltransferase activity | |
Molecular Function | polyprenyltransferase activity | |
Biological Process | glycerophospholipid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGeranylgeranylglyceryl phosphate synthase
- EC number
- Short namesGGGP synthase ; GGGPS
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Sulfolobales
Accessions
- Primary accessionA0A8D5U116
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length249
- Mass (Da)27,051
- Last updated2022-01-19 v1
- MD5 Checksum933F73BADAFC81881AC79529D0B798EA
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP024596 EMBL· GenBank· DDBJ | BCU67286.1 EMBL· GenBank· DDBJ | Genomic DNA |