A0A8D3DPK0 · A0A8D3DPK0_SCOMX
- ProteinAcetylcholine receptor subunit gamma
- Genechrng
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids383 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Catalytic activity
- K+(in) = K+(out)
- Na+(in) = Na+(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | postsynaptic membrane | |
Molecular Function | acetylcholine-gated monoatomic cation-selective channel activity | |
Molecular Function | transmembrane signaling receptor activity |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAcetylcholine receptor subunit gamma
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Carangaria > Pleuronectiformes > Pleuronectoidei > Scophthalmidae > Scophthalmus
Accessions
- Primary accessionA0A8D3DPK0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Postsynaptic cell membrane ; Multi-pass membrane protein
Synaptic cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 260-283 | Helical | ||||
Sequence: LFYIINIIAPCVLFSSLCLLVYYL | ||||||
Transmembrane | 295-314 | Helical | ||||
Sequence: SVATLLGQTVFLFLIAKKVP | ||||||
Transmembrane | 326-347 | Helical | ||||
Sequence: YLMFVMSVTTMVVMNCVIVLNV |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 40-259 | Neurotransmitter-gated ion-channel ligand-binding | ||||
Sequence: GELFKDLMKGYNKNVRPMEKSGDITPVHIKLTLTNLISLNEKEEALMTSVWIEMQWCDYRLRWDQPPRSALYGNITSELRIPSKSIWLPDVILENNVDGQFEVALYCNALVSPNGCVYWLPPAIYRSACAITVNYFPFDWQNCTMVFRSQTYSANEIELVLKQEDNHTLEWVDIDPEAFTENGEWVIKHRPAKKVINSQYTKDEREYQEVVFFLIIQRKP | ||||||
Domain | 266-367 | Neurotransmitter-gated ion-channel transmembrane | ||||
Sequence: IIAPCVLFSSLCLLVYYLPAKAGGQKCTMSVATLLGQTVFLFLIAKKVPETSRAVPLIGKYLMFVMSVTTMVVMNCVIVLNVSLRTPNTHIMTDKVRKVSLR |
Sequence similarities
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length383
- Mass (Da)43,760
- Last updated2022-01-19 v1
- Checksum66E9C136E64ED297