A0A8D2GDU7 · A0A8D2GDU7_THEGE
- ProteinSAM and SH3 domain containing 1
- GeneSASH1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1207 (go to sequence)
- Protein existencePredicted
- Annotation score1/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | mitogen-activated protein kinase kinase kinase binding | |
Biological Process | positive regulation of non-canonical NF-kappaB signal transduction |
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineagecellular organisms > Eukaryota (eucaryotes) > Opisthokonta > Metazoa (metazoans) > Eumetazoa > Bilateria > Deuterostomia > Chordata (chordates) > Craniata > Vertebrata (vertebrates) > Gnathostomata (jawed vertebrates) > Teleostomi > Euteleostomi (bony vertebrates) > Sarcopterygii > Dipnotetrapodomorpha > Tetrapoda (tetrapods) > Amniota (amniotes) > Mammalia (mammals) > Theria > Eutheria (placentals) > Boreoeutheria > Euarchontoglires > Primates > Haplorrhini > Simiiformes > Catarrhini > Cercopithecoidea > Cercopithecidae (Old World monkeys) > Cercopithecinae > Theropithecus
Accessions
- Primary accessionA0A8D2GDU7
Proteomes
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 81-100 | Disordered | ||||
Sequence: VERKNPLHKSNSEDNSVGKG | ||||||
Compositional bias | 82-100 | Basic and acidic residues | ||||
Sequence: ERKNPLHKSNSEDNSVGKG | ||||||
Region | 176-211 | Disordered | ||||
Sequence: AALDPADWPDGSYPTFDGSSNCNSREQSDDETEESV | ||||||
Region | 271-299 | Disordered | ||||
Sequence: FFDGSPEKPPEDDSDSLTTSPSSSSLDTW | ||||||
Compositional bias | 285-299 | Polar residues | ||||
Sequence: DSLTTSPSSSSLDTW | ||||||
Region | 404-528 | Disordered | ||||
Sequence: SLGKKVKSVKETMRKRMSKKYSSSVSEQDSGLDGMPGSPPPSQPDPEHLDKPKLKAGGSVESLRSSLSGQSSMSGQTVSTTDSSASNRESVKSEDGDDEEPPYRGPFCGRARVHTDFTPSPYDTD | ||||||
Compositional bias | 464-490 | Polar residues | ||||
Sequence: ESLRSSLSGQSSMSGQTVSTTDSSASN | ||||||
Compositional bias | 491-508 | Basic and acidic residues | ||||
Sequence: RESVKSEDGDDEEPPYRG | ||||||
Domain | 509-570 | SH3 | ||||
Sequence: PFCGRARVHTDFTPSPYDTDSLKLKKGDIIDIISKPPMGTWMGLLNNKVGTFKFIYVDVLSE | ||||||
Region | 571-594 | Disordered | ||||
Sequence: DEEKPKRPTRRRRKGRPPQPKSVE | ||||||
Domain | 588-652 | SAM | ||||
Sequence: PQPKSVEDLLDRINLKEHMPTFLFNGYEDLDTFKLLEEEDLDELNIRDPEHRAVLLTAVELLQEY | ||||||
Compositional bias | 668-724 | Polar residues | ||||
Sequence: DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSAEPNLKSFSRNQLGNYPTL | ||||||
Region | 668-765 | Disordered | ||||
Sequence: DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSAEPNLKSFSRNQLGNYPTLPLTKSGDALKQGQEEGRLGGGLAPDTSKSCDPPSVTGLNKN | ||||||
Region | 783-838 | Disordered | ||||
Sequence: PQTVDTWPRSHSLDDLQAEPGAEQDVPTEVTEPPPQIVPKVPQKMTASSTKAQPLE | ||||||
Compositional bias | 824-838 | Polar residues | ||||
Sequence: PQKMTASSTKAQPLE | ||||||
Region | 866-885 | Disordered | ||||
Sequence: LEGSIAASGRSLSPPQCLPR | ||||||
Region | 931-1025 | Disordered | ||||
Sequence: VPEARTQPKIPSQPPPVPAKKSRERLANGLYPVPMGPSGTLPSPDAPCLPVKRGSPTSPTSPSDCPPALAPRPLSGQAPGSPPSTRPPPWLSELP | ||||||
Compositional bias | 990-1020 | Pro residues | ||||
Sequence: TSPSDCPPALAPRPLSGQAPGSPPSTRPPPW | ||||||
Domain | 1137-1201 | SAM | ||||
Sequence: GCISSVSDWLISIGLPMYASTLSTAGFSTLSQVPSLSHTCLQEAGITEERHIRKLLSAARLFKLP |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,207
- Mass (Da)132,967
- Last updated2022-01-19 v1
- ChecksumEB74D7792B28B31F
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8D2GDV6 | A0A8D2GDV6_THEGE | SASH1 | 662 | ||
A0A8D2GID9 | A0A8D2GID9_THEGE | SASH1 | 1208 | ||
A0A8D2GBW7 | A0A8D2GBW7_THEGE | SASH1 | 1246 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 82-100 | Basic and acidic residues | ||||
Sequence: ERKNPLHKSNSEDNSVGKG | ||||||
Compositional bias | 285-299 | Polar residues | ||||
Sequence: DSLTTSPSSSSLDTW | ||||||
Compositional bias | 464-490 | Polar residues | ||||
Sequence: ESLRSSLSGQSSMSGQTVSTTDSSASN | ||||||
Compositional bias | 491-508 | Basic and acidic residues | ||||
Sequence: RESVKSEDGDDEEPPYRG | ||||||
Compositional bias | 668-724 | Polar residues | ||||
Sequence: DSQGLSGCSPRDSGCYESSENLENGKTRKASLLSAKSSAEPNLKSFSRNQLGNYPTL | ||||||
Compositional bias | 824-838 | Polar residues | ||||
Sequence: PQKMTASSTKAQPLE | ||||||
Compositional bias | 990-1020 | Pro residues | ||||
Sequence: TSPSDCPPALAPRPLSGQAPGSPPSTRPPPW |
Keywords
- Technical term