A0A8D2FT62 · A0A8D2FT62_THEGE

Function

function

Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).

Catalytic activity

Pathway

Amino-acid degradation; 4-aminobutanoate degradation.

Features

Showing features for active site.

153550100150200250300350400450500
TypeIDPosition(s)Description
Active site306

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionsuccinate-semialdehyde dehydrogenase (NAD+) activity
Biological Processgamma-aminobutyric acid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Succinate-semialdehyde dehydrogenase
  • EC number

Gene names

    • Name
      ALDH5A1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Theropithecus

Accessions

  • Primary accession
    A0A8D2FT62

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain71-530Aldehyde dehydrogenase

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    535
  • Mass (Da)
    57,020
  • Last updated
    2022-01-19 v1
  • Checksum
    163D0E7E3E142367
MATCFWLRSCGARRLGSTFPGCRLHPRAGGLVPAPGPAPGPAQLRAYAGGLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAVLGMVADCGVSEARAAVRAAYEAFCSWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIYTPAKDKRALVLKQPVGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPPGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGALASKFRNTGQTCVCSNRFLVQRGIHDAFVKAFAEAMKKNLHVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATIVTGGKRHHLGKNFFEPTLLSNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANATDVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8D2FUG5A0A8D2FUG5_THEGEALDH5A1507

Keywords

Genome annotation databases

Similar Proteins

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