A0A8D2ER51 · A0A8D2ER51_THEGE
- ProteinUridine-cytidine kinase
- GeneUCKL1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids547 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + cytidine = ADP + CMP + H+
Pathway
Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.
Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | kinase activity | |
Biological Process | CTP salvage | |
Biological Process | UMP salvage |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridine-cytidine kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Theropithecus
Accessions
- Primary accessionA0A8D2ER51
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-90 | Disordered | ||||
Sequence: MAAPPARADADPSPTSPPTARDPPGRQAEKSETACEDRNAESLDRLLPPVGTGHSPRKRTTSQCKSEPPLLRTSKRTIYTAGRPPWYNEH | ||||||
Compositional bias | 25-43 | Basic and acidic residues | ||||
Sequence: GRQAEKSETACEDRNAESL | ||||||
Compositional bias | 55-70 | Polar residues | ||||
Sequence: SPRKRTTSQCKSEPPL | ||||||
Domain | 100-286 | Phosphoribulokinase/uridine kinase | ||||
Sequence: IGLGGGSASGKTTVARMIIEALDVPWVVLLSMDSFYKVLTEQQQEQAAHNNFNFDHPDAFDFDLIISTLKKLKQGKSVKVPVYDFTTHSRKRDWKTLYGANVIIFEGIMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPSFDQYIQPTMRLADIVVPRGSGNTV |
Sequence similarities
Belongs to the uridine kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length547
- Mass (Da)61,045
- Last updated2022-01-19 v1
- Checksum184A616CD58A7802
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 25-43 | Basic and acidic residues | ||||
Sequence: GRQAEKSETACEDRNAESL | ||||||
Compositional bias | 55-70 | Polar residues | ||||
Sequence: SPRKRTTSQCKSEPPL |
Keywords
- Technical term