A0A8D2EMF6 · A0A8D2EMF6_THEGE
- ProteinSodium-coupled monocarboxylate transporter 1
- GeneSLC5A8
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids611 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- (R)-3-hydroxybutanoate(out) + 2 Na+(out) = (R)-3-hydroxybutanoate(in) + 2 Na+(in)(R)-3-hydroxybutanoate (out)CHEBI:10983
+ 2 Na+ (out)CHEBI:29101= CHEBI:10983 + 2 Na+ (in)CHEBI:29101 - (S)-lactate(out) + 2 Na+(out) = (S)-lactate(in) + 2 Na+(in)
- 2 Na+(out) + nicotinate(out) = 2 Na+(in) + nicotinate(in)
- 2 Na+(out) + propanoate(out) = 2 Na+(in) + propanoate(in)
- 2 Na+(out) + pyruvate(out) = 2 Na+(in) + pyruvate(in)
- 4-methyl-2-oxopentanoate(out) + 2 Na+(out) = 4-methyl-2-oxopentanoate(in) + 2 Na+(in)
- 5-oxo-L-proline(out) + 2 Na+(out) = 5-oxo-L-proline(in) + 2 Na+(in)
- acetate(out) + 2 Na+(out) = acetate(in) + 2 Na+(in)
- acetoacetate(out) + 2 Na+(out) = acetoacetate(in) + 2 Na+(in)
- bromide(in) = bromide(out)
- butanoate(out) + 2 Na+(out) = butanoate(in) + 2 Na+(in)
- chloride(in) = chloride(out)
- iodide(out) = iodide(in)
- nitrate(in) = nitrate(out)
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apical plasma membrane | |
Molecular Function | transmembrane transporter activity | |
Biological Process | sodium ion transport |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameSodium-coupled monocarboxylate transporter 1
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Cercopithecidae > Cercopithecinae > Theropithecus
Accessions
- Primary accessionA0A8D2EMF6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Apical cell membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 12-34 | Helical | ||||
Sequence: VWDYVVFAGMLVISAAIGIYYAF | ||||||
Transmembrane | 54-72 | Helical | ||||
Sequence: AVPVALSLTASFMSAVTVL | ||||||
Transmembrane | 84-108 | Helical | ||||
Sequence: IFSIFAFTYFFVVVISAEVFLPVFY | ||||||
Transmembrane | 129-150 | Helical | ||||
Sequence: LCGTVLFIVQTILYTGIVIYAP | ||||||
Transmembrane | 162-182 | Helical | ||||
Sequence: LWGAVVATGVVCTFYCTLGGL | ||||||
Transmembrane | 194-218 | Helical | ||||
Sequence: GIMVAGFASVIIQAAVIQGGISTIL | ||||||
Transmembrane | 240-259 | Helical | ||||
Sequence: HTFWTIIIGGTFTWSSIYGV | ||||||
Transmembrane | 280-302 | Helical | ||||
Sequence: LYINLVGLWAILTCSVFCGLALY | ||||||
Transmembrane | 340-369 | Helical | ||||
Sequence: LFVACAYSGTLSTVSSSINALAAVTVEDLI | ||||||
Transmembrane | 390-410 | Helical | ||||
Sequence: VVYGALCIGMAALASLMGALL | ||||||
Transmembrane | 416-436 | Helical | ||||
Sequence: IFGMVGGPLMGLFALGILVPF | ||||||
Transmembrane | 443-463 | Helical | ||||
Sequence: LVGLMAGFATSLWVGIGAQMY | ||||||
Transmembrane | 521-541 | Helical | ||||
Sequence: YLYFSTVGTLVTLLVGILVSL |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length611
- Mass (Da)66,667
- Last updated2022-01-19 v1
- Checksum1669DB25BD238734
Keywords
- Technical term