A0A8D0WN63 · A0A8D0WN63_PIG
- Proteinmitogen-activated protein kinase kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids547 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | MAP kinase kinase activity | |
Molecular Function | protein tyrosine kinase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namemitogen-activated protein kinase kinase
- EC number
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Suina > Suidae > Sus
Accessions
- Primary accessionA0A8D0WN63
Proteomes
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 53-99 | Disordered | ||||
Sequence: PGLGAWRPQSPVPAQTTLTSPSVCAPARGRPRPLRPGNVHGPVADPT | ||||||
Domain | 153-417 | Protein kinase | ||||
Sequence: LVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMPEKEPRRTHELPGADAGQSSTVYRERSTVSKGRRRFHSAELLTQSLQGNRPFAGPSPGFQLYSSAGAPRL | ||||||
Region | 350-376 | Disordered | ||||
Sequence: KEPRRTHELPGADAGQSSTVYRERSTV | ||||||
Region | 478-499 | Disordered | ||||
Sequence: QGGHRAPPSSRGQGPAGGAIPD | ||||||
Region | 520-547 | Disordered | ||||
Sequence: GLSEPPGPALKIQRPGSSRCGSAVNEPN |
Sequence similarities
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length547
- Mass (Da)59,689
- Last updated2022-01-19 v1
- ChecksumE8CCF26499505DB7