A0A8C9L3G9 · A0A8C9L3G9_PAVCR
- ProteinCytosolic purine 5'-nucleotidase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids549 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- AMP + inosine = adenosine + IMP
- CMP + inosine = cytidine + IMP
- GMP + H2O = guanosine + phosphateThis reaction proceeds in the forward direction.
- GMP + inosine = guanosine + IMP
- H2O + XMP = phosphate + xanthosineThis reaction proceeds in the forward direction.
- dGMP + H2O = 2'-deoxyguanosine + phosphateThis reaction proceeds in the forward direction.
- dGMP + inosine = 2'-deoxyguanosine + IMP
- dIMP + H2O = 2'-deoxyinosine + phosphateThis reaction proceeds in the forward direction.
- dIMP + inosine = 2'-deoxyinosine + IMP
- inosine + UMP = IMP + uridine
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for active site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 5'-nucleotidase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | transferase activity | |
Biological Process | adenosine metabolic process | |
Biological Process | GMP metabolic process | |
Biological Process | IMP metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCytosolic purine 5'-nucleotidase
- EC number
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Pavo
Accessions
- Primary accessionA0A8C9L3G9
Proteomes
Subcellular Location
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 475-549 | Disordered | ||||
Sequence: HVDINEKESPMATRNRTSVDFKDSDYKRHQLTRSISEIKPPNLFPQAPQEITHCHDEDDDEEEEEEEEEEEEEEE | ||||||
Compositional bias | 492-508 | Basic and acidic residues | ||||
Sequence: SVDFKDSDYKRHQLTRS | ||||||
Compositional bias | 529-549 | Acidic residues | ||||
Sequence: HDEDDDEEEEEEEEEEEEEEE |
Sequence similarities
Belongs to the 5'(3')-deoxyribonucleotidase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length549
- Mass (Da)63,696
- Last updated2022-01-19 v1
- ChecksumBC99DF878937DCD5
Computationally mapped potential isoform sequences
There are 4 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8C9EKL4 | A0A8C9EKL4_PAVCR | 581 | |||
A0A8C9EKU2 | A0A8C9EKU2_PAVCR | 459 | |||
A0A8C9EKW0 | A0A8C9EKW0_PAVCR | 539 | |||
A0A8C9EKK3 | A0A8C9EKK3_PAVCR | 578 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 492-508 | Basic and acidic residues | ||||
Sequence: SVDFKDSDYKRHQLTRS | ||||||
Compositional bias | 529-549 | Acidic residues | ||||
Sequence: HDEDDDEEEEEEEEEEEEEEE |
Keywords
- Technical term