A0A8C6MJJ3 · A0A8C6MJJ3_MOSMO
- ProteinDual specificity mitogen-activated protein kinase kinase 2
- GeneMAP2K2
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids400 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 101 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | early endosome | |
Cellular Component | focal adhesion | |
Cellular Component | late endosome | |
Cellular Component | mitochondrion | |
Molecular Function | ATP binding | |
Molecular Function | MAP kinase kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | protein phosphorylation | |
Biological Process | regulation of early endosome to late endosome transport | |
Biological Process | regulation of Golgi inheritance | |
Biological Process | regulation of stress-activated MAPK cascade |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDual specificity mitogen-activated protein kinase kinase 2
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Moschidae > Moschus
Accessions
- Primary accessionA0A8C6MJJ3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 72-369 | Protein kinase | |||
Region | 286-310 | Disordered | |||
Sequence similarities
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length400
- Mass (Da)44,502
- Last updated2022-01-19 v1
- ChecksumFF7CDABD0A943BD4
Keywords
- Technical term