A0A8C3KYB1 · A0A8C3KYB1_CHRPC
- Proteinaldehyde oxidase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1337 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- retinal + O2 + H2O = retinoate + H2O2 + H+
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
Note: Binds 2 [2Fe-2S] clusters.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 49 | [2Fe-2S] cluster 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 54 | [2Fe-2S] cluster 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 57 | [2Fe-2S] cluster 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 79 | [2Fe-2S] cluster 1 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 119 | [2Fe-2S] cluster 2 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 122 | [2Fe-2S] cluster 2 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 154 | [2Fe-2S] cluster 2 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 156 | [2Fe-2S] cluster 2 (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 266-273 | FAD (UniProtKB | ChEBI) | ||||
Sequence: LVVGNTGV | ||||||
Binding site | 356-360 | FAD (UniProtKB | ChEBI) | ||||
Sequence: SLGGN | ||||||
Binding site | 369 | FAD (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 413 | FAD (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 431 | FAD (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 778 | Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI) | ||||
Sequence: Q | ||||||
Binding site | 809 | Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 923 | Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 925 | substrate | ||||
Sequence: F | ||||||
Binding site | 1090 | Mo (UniProtKB | ChEBI) of Mo-molybdopterin (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Active site | 1272 | Proton acceptor | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | 2 iron, 2 sulfur cluster binding | |
Molecular Function | aldehyde oxidase activity | |
Molecular Function | FAD binding | |
Molecular Function | iron ion binding | |
Molecular Function | NAD binding | |
Biological Process | lipid metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namealdehyde oxidase
- EC number
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Chrysolophus
Accessions
- Primary accessionA0A8C3KYB1
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 10-97 | 2Fe-2S ferredoxin-type | ||||
Sequence: AELIFYVNGRKIIEKNADPEQMLLFYLRKRLRLTGTKYGCGGGGCGACTVMISTYEPASKKIRHYSANACLLPICSLYGMAVTTVEGV | ||||||
Domain | 238-423 | FAD-binding PCMH-type | ||||
Sequence: FHGERMMWISPVTLDELQDLKAAHPKAPLVVGNTGVGPDMKFRGVFHPIVIAPARIPDLNVVKCMSDGLTIGAACSLSLMKDVLRNAILELPEEKTKIFYAVLQQLRTLGGEQIRNVASLGGNIISRKSTSDLNPILAAGNCMLNLASQGGKRWIPLSDIFANGVGNNAIMPEEVLVSVHIPHSRK |
Sequence similarities
Belongs to the xanthine dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,337
- Mass (Da)147,740
- Last updated2022-01-19 v1
- Checksum2DDEBD31E6421596
Computationally mapped potential isoform sequences
There are 9 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8C3KYW7 | A0A8C3KYW7_CHRPC | 1342 | |||
A0A8C3KYG0 | A0A8C3KYG0_CHRPC | 1278 | |||
A0A8C3KYX8 | A0A8C3KYX8_CHRPC | 1269 | |||
A0A8C3KZ67 | A0A8C3KZ67_CHRPC | 1273 | |||
A0A8C3PVP5 | A0A8C3PVP5_CHRPC | 1270 | |||
A0A8C3PVP7 | A0A8C3PVP7_CHRPC | 1276 | |||
A0A8C3PVA9 | A0A8C3PVA9_CHRPC | 1270 | |||
A0A8C3PVB4 | A0A8C3PVB4_CHRPC | 1279 | |||
A0A8C3L2Q7 | A0A8C3L2Q7_CHRPC | 1271 |
Keywords
- Technical term