A0A8C2NG12 · A0A8C2NG12_CAPHI
- ProteinGlycogen synthase kinase-3 beta
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids415 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
Catalytic activity
- L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 86 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | axon | |
Cellular Component | beta-catenin destruction complex | |
Cellular Component | cytosol | |
Cellular Component | glutamatergic synapse | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | beta-catenin binding | |
Molecular Function | protein serine/threonine kinase activity | |
Molecular Function | tau-protein kinase activity | |
Biological Process | extrinsic apoptotic signaling pathway in absence of ligand | |
Biological Process | glycogen metabolic process | |
Biological Process | insulin receptor signaling pathway | |
Biological Process | negative regulation of canonical Wnt signaling pathway | |
Biological Process | negative regulation of developmental process | |
Biological Process | protein phosphorylation | |
Biological Process | regulation of microtubule cytoskeleton organization | |
Biological Process | regulation of neuron projection development |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycogen synthase kinase-3 beta
- EC number
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Caprinae > Capra
Accessions
- Primary accessionA0A8C2NG12
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-25 | Polar residues | |||
Region | 1-53 | Disordered | |||
Domain | 56-340 | Protein kinase | |||
Sequence similarities
Family and domain databases
Sequence
- Sequence statusComplete
- Length415
- Mass (Da)46,683
- Last updated2022-01-19 v1
- Checksum08519C5A44DC14E3
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-25 | Polar residues | |||