A0A8C0Z504 · A0A8C0Z504_CANLF
- ProteinMetalloendopeptidase
- GeneBMP1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids988 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 215 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 216 | ||||
Binding site | 219 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 225 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | calcium ion binding | |
Molecular Function | identical protein binding | |
Molecular Function | metalloendopeptidase activity | |
Molecular Function | zinc ion binding | |
Biological Process | positive regulation of cartilage development | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMetalloendopeptidase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Canis
Accessions
- Primary accessionA0A8C0Z504
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-24 | ||||
Chain | PRO_5042658673 | 25-988 | Metalloendopeptidase | ||
Disulfide bond | 185↔207 | ||||
Disulfide bond | 187↔188 | ||||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 82-109 | Polar residues | |||
Region | 82-127 | Disordered | |||
Domain | 123-322 | Peptidase M12A | |||
Domain | 324-436 | CUB | |||
Domain | 437-549 | CUB | |||
Domain | 549-590 | EGF-like | |||
Domain | 593-705 | CUB | |||
Domain | 749-861 | CUB | |||
Domain | 862-978 | CUB | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length988
- Mass (Da)111,786
- Last updated2022-01-19 v1
- ChecksumDD17B0E27441EA88
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 82-109 | Polar residues | |||