A0A8C0VIP9 · A0A8C0VIP9_CYACU
- ProteinCarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
- GeneCAD
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids2014 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- hydrogencarbonate + L-glutamine + 2 ATP + H2O = carbamoyl phosphate + L-glutamate + 2 ADP + phosphate + 2 H+
Cofactor
Pathway
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | amino acid binding | |
Molecular Function | aspartate carbamoyltransferase activity | |
Molecular Function | ATP binding | |
Molecular Function | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | |
Molecular Function | dihydroorotase activity | |
Molecular Function | metal ion binding | |
Biological Process | 'de novo' pyrimidine nucleobase biosynthetic process | |
Biological Process | 'de novo' UMP biosynthetic process | |
Biological Process | citrulline biosynthetic process | |
Biological Process | glutamine metabolic process | |
Biological Process | UTP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Paridae > Cyanistes
Accessions
- Primary accessionA0A8C0VIP9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 249-441 | ATP-grasp | |||
Domain | 785-976 | ATP-grasp | |||
Domain | 1041-1198 | MGS-like | |||
Region | 1559-1639 | Disordered | |||
Compositional bias | 1598-1625 | Basic and acidic residues | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,014
- Mass (Da)220,944
- Last updated2022-01-19 v1
- Checksum085C03DA5AFA5937
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1598-1625 | Basic and acidic residues | |||
Keywords
- Technical term