A0A8C0S078 · A0A8C0S078_CANLF

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site, active site.

1819100200300400500600700800
TypeIDPosition(s)Description
Binding site347Zn2+ (UniProtKB | ChEBI); catalytic
Active site348
Binding site351Zn2+ (UniProtKB | ChEBI); catalytic
Binding site357Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functioncollagen binding
Molecular Functionintegrin binding
Molecular Functionlaminin binding
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Molecular FunctionSH3 domain binding
Biological Processcell-cell adhesion mediated by integrin
Biological Processcell-matrix adhesion
Biological Processcellular response to lipopolysaccharide
Biological Processkeratinocyte differentiation
Biological Processmembrane protein ectodomain proteolysis
Biological Processmembrane protein intracellular domain proteolysis
Biological Processmonocyte activation
Biological Processpositive regulation of cell adhesion mediated by integrin
Biological Processpositive regulation of keratinocyte migration
Biological Processpositive regulation of macrophage fusion
Biological Processpositive regulation of MAP kinase activity
Biological Processpositive regulation of protein secretion
Biological Processresponse to calcium ion
Biological Processresponse to hydrogen peroxide
Biological Processresponse to manganese ion
Biological Processresponse to tumor necrosis factor
Biological Processtransforming growth factor beta receptor signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • ADAM metallopeptidase domain 9

Gene names

    • Name
      ADAM9

Organism names

Accessions

  • Primary accession
    A0A8C0S078

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane699-718Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-28
ChainPRO_504276461329-819
Disulfide bond365↔370
Disulfide bond473↔493
Disulfide bond664↔673

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain212-406Peptidase M12B
Domain414-501Disintegrin
Domain640-674EGF-like
Region734-819Disordered
Compositional bias739-756Polar residues

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    819
  • Mass (Da)
    90,805
  • Last updated
    2022-01-19 v1
  • Checksum
    37DF8DDFA764C324
MGSGAGSPFGVFRLQWLLLFGTVGPVLGGARPGFQQTSHLSSYEIITPWRLTRERREAPRPYSEQVSYIIQAEGKEHIIHLERNNDFLPRDFVVYTYNKEGALISDHPDVQNHCHYRGYVEGISNSSIALSDCFGLRGLLHIENVSYGIEPLQNSSHFEHIFYRMDDVHKEPLKCGVSNKDMEKETTNYEEEEPLSVTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMIRLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIIGGAGDVLGNFVQWREKFLITRRRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRDCFCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPFCGNKLVDPGEECDCGTPKECESDPCCEGTTCKLKSSAECAYGDCCKDCWFLPGGTLCRGKTNECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQVIFGSKAKAAPRDCFIDVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQDMPVFGIVPAIIQTPSKGTKCWGVDFQLGSDVPDPGMVNEGTRCDNGKICRNFQCVNASVLNYDCDIQKKCHGHGVCNSNKNCHCENGWAPPNCETKGYGGSVDSGPTYNEKNTALRDGLLVFFFLIVPLIVCAAFVFIKRDQLWRSYFQKKRSQTYESDGKNQAKASRQPVSVPRHVSSVTPPREAPIYANRFPVPTYAAKQPQQFPSRPPPPQPKVSSQGNLIPARPAPAPPLYSSLT

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias739-756Polar residues

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

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