A0A8C0QH50 · A0A8C0QH50_CANLF
- ProteinPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha
- GenePIP4K2A
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids392 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + ATP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ADP + H+This reaction proceeds in the forward direction.
- 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate) + GTP = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + GDP + H+This reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | lysosome | |
Cellular Component | nucleus | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | phosphatidylinositol kinase activity | |
Biological Process | phosphatidylinositol metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphatidylinositol 5-phosphate 4-kinase type-2 alpha
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Canis
Accessions
- Primary accessionA0A8C0QH50
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 33-392 | PIPK | ||||
Sequence: ASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHESWCRDLDREPRTVFKALFGLYWPHLDVTSHMALDGHEPGKEREVASV | ||||||
Compositional bias | 288-302 | Acidic residues | ||||
Sequence: QEEVECEENDGEEEG | ||||||
Region | 288-329 | Disordered | ||||
Sequence: QEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAP |
Family and domain databases
Sequence
- Sequence statusComplete
- Length392
- Mass (Da)44,835
- Last updated2022-01-19 v1
- Checksum35E40431E5CC2443
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 288-302 | Acidic residues | ||||
Sequence: QEEVECEENDGEEEG |