A0A8C0M0G9 · A0A8C0M0G9_CANLF

Function

Catalytic activity

GO annotations

AspectTerm
Cellular Componentbicellular tight junction
Cellular Componentcell body
Cellular Componentcytoplasm
Cellular Componentprotein-containing complex
Molecular FunctionATP binding
Molecular Functionchloride ion binding
Molecular Functionion channel inhibitor activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processaldosterone secretion
Biological Processcalcium ion homeostasis
Biological Processcellular response to xenobiotic stimulus
Biological Processchloride transport
Biological Processdistal tubule morphogenesis
Biological ProcessERK1 and ERK2 cascade
Biological Processgene expression
Biological Processinflammatory response
Biological Processintracellular chloride ion homeostasis
Biological Processmacrophage activation
Biological Processnegative regulation of pancreatic juice secretion
Biological Processnegative regulation of protein localization to plasma membrane
Biological Processpotassium ion transmembrane transport
Biological Processprotein kinase C signaling
Biological Processprotein localization
Biological Processprotein phosphorylation
Biological Processregulation of blood pressure
Biological Processregulation of potassium ion export across plasma membrane
Biological Processrenal sodium ion absorption
Biological Processresponse to dietary excess
Biological Processsodium ion transmembrane transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    non-specific serine/threonine protein kinase
  • EC number

Gene names

    • Name
      WNK4

Organism names

Accessions

  • Primary accession
    A0A8C0M0G9

Proteomes

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region30-68Disordered
Region85-251Disordered
Compositional bias128-144Basic and acidic residues
Compositional bias161-190Pro residues
Compositional bias226-246Basic and acidic residues
Domain257-515Protein kinase
Region615-645Disordered
Compositional bias621-639Pro residues
Region713-765Disordered
Region835-917Disordered
Compositional bias863-905Polar residues
Region1027-1185Disordered
Compositional bias1029-1052Pro residues
Compositional bias1107-1133Polar residues
Compositional bias1141-1169Basic and acidic residues
Region1239-1316Disordered
Compositional bias1259-1277Polar residues
Compositional bias1288-1305Polar residues

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,316
  • Mass (Da)
    141,439
  • Last updated
    2022-01-19 v1
  • Checksum
    D4EF68E134E0BA80
MFPLPAPALSLHHPPPNRFAHSCCGRARCRLAPGPPRNDPAGGCARRRGRGGPAAGGGAAEAASSPAARLAALRRRPFLMLAPPTSETAVPMSQAEADLGLRPPPPLAAAAAAAAGPPRLGPPPRRARRFSGKAEPRPRSSRLSRRSSVDLGLLSLWSQPASPVPEPPDPPDSAGAGPARSPPPSRPEPPEGTWTGGAPVKAADSTRPELPGSTGGPGGRDPQTAPEAAARERQREQEEKEDTETQAVATSPDGRYLKFDIEIGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRTERQRFSEEVEMLKGLQHPNIVRFYDSWKSVLRGQVCIVLVTELMTSGTLKTYLRRFREMKPRVLQRWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPSGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGTKPNSFYKVKMPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREERGVHVELAEEDDGEKPGLKLWLRMEDARRGGRPRDNQAIEFLFQLGRDAAEEVAQEMVALGLVCEADYQPVARAVRERVAAIQRKREKLRKARELEALPPAPGPQAATVPMTPGPPSVFPHEPEEPEADQHQPFLFRHASYSSTTSDCETDGYLSSSGFLDASDPAFQPPGGVPSSPAESHLCLPSAFALSIPRSGPGSDFSPGDSYASDAASGLSDVGEGMACMRRPPGRNLRRRPRSRLRVTSVSDQNDRVVECQLQTHNSKMVTFRFDLDGDSPEEIAAAMVYNEFILPSERAGFLSRIREIIQRVETLLKRDTGPVEAAEDPLGPQEEPVPLPALSSPLPDQSCAELQSSTSLEQRSWAAFSTSSSSPGTPLSPGNLFSPGTPETPVSPSPIFPITSSPYPSPSPFSQVSSNLPQHSPNSLLGFSPSAAQFPVPTSHCLQSSILPSPASSPSCSQSALSPPSFLSCPSTSPLPSTTAAPLLSLASAFSLAVMTVAQSLLSPSPGLLSQSPVAPPGPLPSLPLPAPPAASPPTAEMESEAPPNPARPLLGEARLAPISEEGKPQLVGRFQVTSSKEPAEPLPLQPALPTLSSSLKPPTPQLTSESSDTEDSAGSGPEAREALAESDRAAEGLGAGVEEEGDDGKEPRVGGSPPPHSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAQLQSLRQKHLSEVEALQTLQKKEIEDLYSRLGKQPPPGIVAPAAMLSSRQRRLSKGSFPTSRRNSLQRSEPLGPGIMRRNSLSGSSTGSQEQRASKGVTFAGDVGRM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias128-144Basic and acidic residues
Compositional bias161-190Pro residues
Compositional bias226-246Basic and acidic residues
Compositional bias621-639Pro residues
Compositional bias863-905Polar residues
Compositional bias1029-1052Pro residues
Compositional bias1107-1133Polar residues
Compositional bias1141-1169Basic and acidic residues
Compositional bias1259-1277Polar residues
Compositional bias1288-1305Polar residues

Genome annotation databases

Similar Proteins

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