A0A8B9Y680 · A0A8B9Y680_BOSMU
- ProteinTyrosine-protein kinase
- GeneBTK
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids637 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 408 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | plasma membrane | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | non-membrane spanning protein tyrosine kinase activity | |
Biological Process | adaptive immune response | |
Biological Process | B cell receptor signaling pathway | |
Biological Process | intracellular signal transduction | |
Biological Process | protein phosphorylation | |
Biological Process | T cell receptor signaling pathway |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTyrosine-protein kinase
- EC number
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0A8B9Y680
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 3-133 | PH | |||
Region | 171-196 | Disordered | |||
Domain | 192-252 | SH3 | |||
Domain | 259-355 | SH2 | |||
Domain | 380-633 | Protein kinase | |||
Sequence similarities
Belongs to the protein kinase superfamily. Tyr protein kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length637
- Mass (Da)73,769
- Last updated2022-01-19 v1
- ChecksumFF884BD730421371
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8B9YD17 | A0A8B9YD17_BOSMU | BTK | 646 | ||
A0A8C0AH93 | A0A8C0AH93_BOSMU | BTK | 461 |
Keywords
- Technical term