A0A8B9WZY7 · A0A8B9WZY7_BOSMU
- ProteinDiamine acetyltransferase 1
- GeneSAT1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids143 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N1-acetylspermine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Also acts on 1,3-diaminopropane and 1,5-diaminopentane.
Catalytic activity
- an alkane-alpha,omega-diamine + acetyl-CoA = an N-acetylalkane-alpha,omega-diamine + CoA + H+This reaction proceeds in the forward direction.
an alkane-α,ω-diamine RHEA-COMP:9766 + CHEBI:57288 = an N-acetylalkane-α,ω-diamine RHEA-COMP:9767 + CHEBI:57287 + CHEBI:15378
Pathway
Amine and polyamine degradation; putrescine degradation; N-acetylputrescine from putrescine: step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | diamine N-acetyltransferase activity | |
Molecular Function | spermidine binding | |
Biological Process | putrescine catabolic process | |
Biological Process | spermidine acetylation |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDiamine acetyltransferase 1
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos
Accessions
- Primary accessionA0A8B9WZY7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length143
- Mass (Da)16,720
- Last updated2022-01-19 v1
- MD5 ChecksumC5E5F60A3E5E2ABF5E5877CA0A528B20
Computationally mapped potential isoform sequences
There are 2 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8B9WTT5 | A0A8B9WTT5_BOSMU | SAT1 | 171 | ||
A0A8B9WXZ0 | A0A8B9WXZ0_BOSMU | SAT1 | 119 |
Keywords
- Technical term