A0A8B8SV89 · A0A8B8SV89_CAMFR
- ProteinTransmembrane channel-like protein
- GeneTMC1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids788 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | mechanosensitive monoatomic ion channel activity | |
Molecular Function | voltage-gated calcium channel activity | |
Biological Process | detection of mechanical stimulus involved in sensory perception of sound | |
Biological Process | vestibular reflex |
Names & Taxonomy
Protein names
- Recommended nameTransmembrane channel-like protein
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Tylopoda > Camelidae > Camelus
Accessions
- Primary accessionA0A8B8SV89
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 222-244 | Helical | |||
Transmembrane | 303-321 | Helical | |||
Transmembrane | 394-415 | Helical | |||
Transmembrane | 470-490 | Helical | |||
Transmembrane | 663-684 | Helical | |||
Transmembrane | 724-744 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 35-115 | Disordered | |||
Compositional bias | 54-78 | Basic and acidic residues | |||
Compositional bias | 87-108 | Basic and acidic residues | |||
Domain | 543-658 | TMC | |||
Sequence similarities
Belongs to the TMC family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length788
- Mass (Da)90,862
- Last updated2022-01-19 v1
- MD5 Checksum98810E31F06629A176494FC1F729488A
Computationally mapped potential isoform sequences
There are 12 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8B8SVX3 | A0A8B8SVX3_CAMFR | TMC1 | 848 | ||
A0A8B8SVZ2 | A0A8B8SVZ2_CAMFR | TMC1 | 660 | ||
A0A8B8SVY1 | A0A8B8SVY1_CAMFR | TMC1 | 819 | ||
A0A8B8SUE4 | A0A8B8SUE4_CAMFR | TMC1 | 831 | ||
A0A8B8SUF5 | A0A8B8SUF5_CAMFR | TMC1 | 784 | ||
A0A8B8SV99 | A0A8B8SV99_CAMFR | TMC1 | 654 | ||
A0A8B8SV94 | A0A8B8SV94_CAMFR | TMC1 | 780 | ||
A0A8B8SUU8 | A0A8B8SUU8_CAMFR | TMC1 | 687 | ||
A0A8B8SUL3 | A0A8B8SUL3_CAMFR | TMC1 | 836 | ||
A0A8B8SUL8 | A0A8B8SUL8_CAMFR | TMC1 | 823 | ||
A0A8B8SUM4 | A0A8B8SUM4_CAMFR | TMC1 | 813 | ||
A0A8B8SUN0 | A0A8B8SUN0_CAMFR | TMC1 | 783 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 54-78 | Basic and acidic residues | |||
Compositional bias | 87-108 | Basic and acidic residues | |||
Keywords
- Technical term