Essential maintenance is planned to begin on Fri Jan 24 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ in case of any outage.

A0A8B8ES75 · A0A8B8ES75_CRAVI

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

  • Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.
    EC:3.4.18.1 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Cellular Componentlysosome
Cellular Componentmembrane
Molecular Functioncysteine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    cathepsin X
  • EC number

Gene names

    • Name
      LOC111136303

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Bivalvia > Autobranchia > Pteriomorphia > Ostreida > Ostreoidea > Ostreidae > Crassostrea

Accessions

  • Primary accession
    A0A8B8ES75

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane214-237Helical
Transmembrane473-492Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond184↔199

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region254-284Disordered
Compositional bias262-284Polar residues
Region342-419Disordered
Compositional bias383-419Polar residues
Domain529-762Peptidase C1A papain C-terminal

Sequence similarities

Belongs to the peptidase C1 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    776
  • Mass (Da)
    86,308
  • Last updated
    2022-01-19 v1
  • MD5 Checksum
    24327D9F5AF90D771FF6F21E7755AC48
MMAIAISLCMDSPLEVRHYYDLAVCSFTYSKKEKIDVVSLEYQKKGYDKCEYLIKAPPDSNIIALNFTDLVGFGSAVGGTLPDTYTDPAGSDREALLPCLPPELTISDETPGPHGVVSSKICKSQNYQTPHVFHFKSNVLKIIYVWVEDEQSGFTLDINFHHSFKNCVFTCDGTHCLENKSLICDQVYHCQDKTDEHNCPQSSVGAASTAVTRVVVIIVTITLMPVLAILICVASPCKSTRRMLRRWTNRNHGDVENRQLRPRSQVSEGGFGGAATSTSCVSASQEISDPQEALLRERQILKHSMQTDVTISLPPQIPISQDGEEGYQQSQKTLKYLRKSDGYQHCFRPPPNKTVHDKESPPPYYSHSASALDKVGHSPLKVGGSPNSRTTSSEMLSRSYSMSNSNHYHDPSVARTNNSNMRGSAAIHQELHTSNFEPPNYHTLYNTFDDKVKNHVTLSYDCMTRKMDAVKSVVFLFCLLGAVLSQSEWVSLQASKKYSRRACFKKMYPDEIRVGSSPRPHEFLDLNTLPASWDWRNVNGTNYLSATRNQHIPQYCGSCWGMGSTSAMADRINIKRKGAWPSAYLSVQHVIDCGKAGSCEGGDDVGVWSYAHTHGIPDETCNNYQAKDQDCDAFNQCGTCVTFGKCFQLSNYTLWKVSDYGTVKGRDKMMAEIYKNGPISCGIDATEKLEAYTGGIYTEKKLLPMVNHIVSVAGWGVDPATKTEYWIVRNSWGDPWGEHGFLRIVTSAYNGGKGNDYNLAIESRCAYGDPIIPPGY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias262-284Polar residues
Compositional bias383-419Polar residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help