A0A8B6LEQ1 · A0A8B6LEQ1_9BURK

  • Protein
    Phosphoenolpyruvate-protein phosphotransferase
  • Gene
    ptsI
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for active site, binding site.

160350100150200250300350400450500550600
TypeIDPosition(s)Description
Active site218Tele-phosphohistidine intermediate
Binding site325phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site366phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site466Mg2+ (UniProtKB | ChEBI)
Binding site489-490phosphoenolpyruvate (UniProtKB | ChEBI)
Binding site490Mg2+ (UniProtKB | ChEBI)
Binding site500phosphoenolpyruvate (UniProtKB | ChEBI)
Active site537Proton donor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionkinase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoenolpyruvate-protein phosphotransferase activity
Biological Processphosphoenolpyruvate-dependent sugar phosphotransferase system

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphoenolpyruvate-protein phosphotransferase
  • EC number
  • Alternative names
    • Phosphotransferase system, enzyme I

Gene names

    • Name
      ptsI
    • ORF names
      SRS16CHR_00349

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SRS16
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Comamonadaceae > Variovorax

Accessions

  • Primary accession
    A0A8B6LEQ1

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain6-133Phosphotransferase system enzyme I N-terminal
Region157-176Disordered
Domain183-254PEP-utilising enzyme mobile
Domain281-575PEP-utilising enzyme C-terminal

Sequence similarities

Belongs to the PEP-utilizing enzyme family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    603
  • Mass (Da)
    66,088
  • Last updated
    2021-09-29 v1
  • Checksum
    7144D9FAD949F5BA
MTFAVHGLPVARGIAIGRAVLVVSSRIDVAHYFIKPEQIETEIDRVRTARNAVSEELQKLQASVALMGPNDTPHELAALLDVHQMLLQDEVLTGGVKHWITERLYNAEWALTTQLEVIARQFDEMEDEYLRERKADLEQVVERLLHRMKGTAAVLAPTPPRRKRAAETEEGGDDPVASEAIDAPLVLIAHDLSPADMLQFKKSVFAGFVTDVGGRTSHTAIVARSMDIPAVVGARSASQLVRQDDWVIIDGDTGVMIVDPSPIILAEYGFKQRQGDLERGRLARLRHKPAVTLDGQRVDLLANIEMPEDTIGAVKAGAVGVGLFRSEFLFMGREAQRLTRLPDEEEQYQAYKRAVEGMQGMPVTIRTIDVGADKPLDGKSVRDDAHLNPALGLRAIRWSLADPAMFLTQLRAILRAAAHGEIHLLIPMLAHASEIRQTISLIDFARAELDNRGAVHGAVKLGAMIEIPAAALTLKTFLKHFDFLSIGTNDLIQYTLAIDRADESVAHLYDPAHPAVLRLVADTIAECRRQGKGVSVCGEMAGDIVFTRLLLGLGLRSFSMHPSQILAVKQEVLRADAGKLEAWAQQVLEAEDPAAALMPVPAR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LR594666
EMBL· GenBank· DDBJ
VTU13110.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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