A0A8B3MBY0 · A0A8B3MBY0_ECOLX
- Protein2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase
- GenemhpB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids317 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively.
Catalytic activity
- (2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O2 = (2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H+
Cofactor
Pathway
Aromatic compound metabolism; 3-phenylpropanoate degradation.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 115 | Proton donor | |||
Active site | 179 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-carboxyethylcatechol 2,3-dioxygenase activity | |
Molecular Function | ferrous iron binding | |
Biological Process | 3-phenylpropionate catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionA0A8B3MBY0
Proteomes
Interaction
Subunit
Homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length317
- Mass (Da)34,238
- Last updated2021-09-29 v1
- ChecksumB7ABC6392BEC1DB1
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NPIM01000060 EMBL· GenBank· DDBJ | RVE16355.1 EMBL· GenBank· DDBJ | Genomic DNA |