A0A8B3LT78 · A0A8B3LT78_ECOLX

  • Protein
    Pseudouridine-5'-phosphate glycosidase
  • Gene
    psuG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 1 Mn2+ ion per subunit.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site31Proton donor
Binding site93substrate
Binding site113substrate
Binding site145Mn2+ (UniProtKB | ChEBI)
Binding site147-149substrate
Active site166Nucleophile

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionhydrolase activity, acting on glycosyl bonds
Molecular Functionmetal ion binding
Molecular Functionpseudouridylate synthase activity
Biological Processnucleobase catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pseudouridine-5'-phosphate glycosidase
  • EC number
  • Short names
    PsiMP glycosidase

Gene names

    • Name
      psuG
    • ORF names
      CIG67_25425

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • CCPM 6219
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    A0A8B3LT78

Proteomes

Subcellular Location

Interaction

Subunit

Homotrimer.

Family & Domains

Sequence similarities

Belongs to the pseudouridine-5'-phosphate glycosidase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    312
  • Mass (Da)
    33,050
  • Last updated
    2021-09-29 v1
  • MD5 Checksum
    07FF4EEF0FAD91ED7C8B58A65315DC13
MSKLKISPELLQISPEVQEALKNKKPVVALESTIISHGMPFPQNAQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFVVAAGKNGTTTVASTMIIAALAGIKVFATGGIGGVHRRAEHTFDISADLQELANTNVTVVCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSSFDVSIRLDSASEIARAMAVKWQSGLNGGLVVANPIPEQFAMPEESINAAIDQAVAEAEEQGVIGKESTPFLLARVAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NPIM01000165
EMBL· GenBank· DDBJ
RVE07658.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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