A0A8A3S1D6 · A0A8A3S1D6_9EURY

  • Protein
    Protein-glutamate methylesterase/protein-glutamine glutaminase
  • Gene
    cheB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site153
Active site180
Active site281

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmethyltransferase activity
Molecular Functionphosphorelay response regulator activity
Molecular Functionprotein-glutamate methylesterase activity
Molecular Functionprotein-glutamine glutaminase activity
Biological Processchemotaxis
Biological Processmethylation
Biological Processprotein deamination
Biological Processprotein demethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-glutamate methylesterase/protein-glutamine glutaminase
  • EC number

Gene names

    • Name
      cheB
    • ORF names
      RJ40_01615

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • N2F9704
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Methanomicrobia > Methanomicrobiales > Methanomicrobiaceae > Methanofollis

Accessions

  • Primary accession
    A0A8A3S1D6

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue544-aspartylphosphate

Post-translational modification

Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-121Response regulatory
Domain141-339CheB-type methylesterase

Domain

Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.

Sequence similarities

Belongs to the CheB family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    344
  • Mass (Da)
    37,107
  • Last updated
    2021-09-29 v1
  • Checksum
    ADC6C465C0E33995
MIRVLIVDDSVFIRTILKDIFGKSPEIEVVGTASDGAEALELIDTLRPDAMTLDIEMPKLNGLEVLERMKECQHRPKVMMLSSLTAKDAEHTRKALALGADDFMLKPTEIFKVRGIEEELVTRIKHLIEIKTAVKVRGRRDRVAGKVVLFGSSAGGLQQLDLVLSRLSSELDAAVVVTQHMPAGFTAALAERFNRICPLPVRESENGSVLKEGEVVISKAGFHTVISAILTGEGTRGGKIIHSSAPPVHAVRPAIDKTFSSAAKVFGERTLAVVMSGMGSDCGDGAADIKAAGGTVYVCKEHDCLVYGMARSALKKSSVDQTVSLRHIPEEVVKAVRRMEAEDG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP036172
EMBL· GenBank· DDBJ
QSZ66287.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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