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A0A8A3NUB2 · A0A8A3NUB2_9HELO

  • Protein
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

Catalytic activity

GO annotations

AspectTerm
Cellular ComponentmRNA cleavage and polyadenylation specificity factor complex
Molecular FunctionRNA polymerase II CTD heptapeptide repeat phosphatase activity
Biological ProcessmRNA processing
Biological Processtermination of RNA polymerase II transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72
  • EC number
  • Short names
    CTD phosphatase SSU72

Gene names

    • ORF names
      DSL72_003798

Organism names

  • Taxonomic identifier
  • Strain
    • RL-1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Helotiales > Sclerotiniaceae > Monilinia

Accessions

  • Primary accession
    A0A8A3NUB2

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Subunit

Component of the cleavage and polyadenylation factor (CPF) complex.

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias1-20Polar residues
Region1-23Disordered

Sequence similarities

Belongs to the SSU72 phosphatase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    260
  • Mass (Da)
    28,674
  • Last updated
    2021-09-29 v1
  • MD5 Checksum
    0C36377B43C69DAFB7BE097D4B4610E3
MSQAPTSAVNGGTTPQLASNGGRVDPGGFKLKFCTVCASNNNRSMESHLRLAAAHYPVISFGTGSLVRLPGPSITQPNVYQFNKTSYDSMYKELESKDPRLYRANGILNMLGRNRSVKWGPERWQDWQVGVPRLQHSTDQGAEGVEGGVVDIVITCEERCWDAVVDDLLNRGSPLNRPVHVINVDIKDNHEEALVGGRGILDLADSLNKAAVEERELNPIGFDSGSSSSRAGFDERVPEIIGEWQERWPNLPAVWTLSWF

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-20Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP063405
EMBL· GenBank· DDBJ
QSZ29285.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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