A0A8A2H8X2 · A0A8A2H8X2_9ACAR

  • Protein
    Cytochrome b
  • Gene
    CYTB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Cofactor

Protein has several cofactor binding sites:
heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme groups non-covalently.
heme (UniProtKB | Rhea| CHEBI:30413 )

Note: Binds 2 heme groups non-covalently.

Features

Showing features for binding site.

136050100150200250300350
TypeIDPosition(s)Description
Binding site75Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site89Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site174Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site188Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site193a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentrespiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b

Gene names

    • Name
      CYTB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • TKL1
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Parasitiformes > Ixodida > Ixodoidea > Ixodidae > Rhipicephalinae > Dermacentor

Accessions

  • Primary accession
    A0A8A2H8X2

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-48Helical
Transmembrane69-90Helical
Transmembrane102-125Helical
Transmembrane137-158Helical
Transmembrane170-191Helical
Transmembrane221-240Helical
Transmembrane280-299Helical
Transmembrane315-335Helical
Transmembrane341-359Helical

Keywords

Interaction

Subunit

The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-201Cytochrome b/b6 N-terminal region profile
Domain202-360Cytochrome b/b6 C-terminal region profile

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    360
  • Mass (Da)
    41,413
  • Last updated
    2021-09-29 v1
  • Checksum
    BA6F9E5524F048D7
MMINKFLHPMVNLPTPSNISYMWNFGSLLGICLMSQILTGLFLAMNFSSDISTAFLMISHIQRDVNNGWLIRSIHANGASLFFILIYFHIGRGIYYSSFHFIKVWISGILIIFILMATAFLGYILPWGQMSFWGATVITNLISAIPYIGMSMTFWIWGGFSVENNTLIRFFSLHFLLPFVLLSLVMIHILLIHTKGSSNPLGVSMNIDKISFHPYFSIKDILGILMVLLLFASVSILWPYNLMDAENFNIANPMITPPHIQPEWYFLFAYAILRSIPNKLGGVLALVMSIIIVVSFSFTMNKKFSSFYFNKKNKILFWFLINCFLMLTYLGAMPIEYPYDLMSKIFTILYFMMFIIIPMT

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MW034677
EMBL· GenBank· DDBJ
QSV37420.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp