A0A899J417 · A0A899J417_9TELE
- ProteinRhodopsin
- Generhod
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids233 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).
Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling
Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling
Features
Showing features for site, binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | photoreceptor outer segment | |
Molecular Function | G protein-coupled photoreceptor activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular response to light stimulus | |
Biological Process | phototransduction | |
Biological Process | visual perception |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameRhodopsin
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Perciformes > Serranoidei > Serranidae > Serraninae > Serranus
Accessions
- Primary accessionA0A899J417
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 21-42 | Helical | ||||
Sequence: YILLNLAVANLFMVLGGFTTTM | ||||||
Transmembrane | 62-80 | Helical | ||||
Sequence: FFATLGGEMALWSLVVLAI | ||||||
Transmembrane | 101-120 | Helical | ||||
Sequence: IMGLGFCWTMASACAVPPLV | ||||||
Transmembrane | 150-170 | Helical | ||||
Sequence: FVIYMFVCHFMIPLVVIFFCY | ||||||
Transmembrane | 201-223 | Helical | ||||
Sequence: VVMMVVAFLVCWCPYAGVAWWIF |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Disulfide bond | 57↔134 | |||||
Sequence: CNLEGFFATLGGEMALWSLVVLAIERWVVVCKPIANFRFGEEHAIMGLGFCWTMASACAVPPLVGWSRYIPEGMQCSC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-215 | G-protein coupled receptors family 1 profile | ||||
Sequence: VNFLTLYVTIEHKKLRTPLNYILLNLAVANLFMVLGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGEMALWSLVVLAIERWVVVCKPIANFRFGEEHAIMGLGFCWTMASACAVPPLVGWSRYIPEGMQCSCGVDYYTRAEGFNNESFVIYMFVCHFMIPLVVIFFCYGRLLCAVKEAAAAQQESETTQRAEREVSRMVVMMVVAFLVCWCPY |
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Keywords
- Domain
Family and domain databases
Protein family/group databases
Sequence
- Sequence statusFragment
- Length233
- Mass (Da)26,235
- Last updated2021-09-29 v1
- Checksum98C0AC58CD85B270
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: V | ||||||
Non-terminal residue | 233 | |||||
Sequence: V |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MW447443 EMBL· GenBank· DDBJ | QSM05915.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447444 EMBL· GenBank· DDBJ | QSM05916.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447445 EMBL· GenBank· DDBJ | QSM05917.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447446 EMBL· GenBank· DDBJ | QSM05918.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447447 EMBL· GenBank· DDBJ | QSM05919.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447448 EMBL· GenBank· DDBJ | QSM05920.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447449 EMBL· GenBank· DDBJ | QSM05921.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447450 EMBL· GenBank· DDBJ | QSM05922.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447451 EMBL· GenBank· DDBJ | QSM05923.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447452 EMBL· GenBank· DDBJ | QSM05924.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447453 EMBL· GenBank· DDBJ | QSM05925.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447454 EMBL· GenBank· DDBJ | QSM05926.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447455 EMBL· GenBank· DDBJ | QSM05927.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447456 EMBL· GenBank· DDBJ | QSM05928.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MW447457 EMBL· GenBank· DDBJ | QSM05929.1 EMBL· GenBank· DDBJ | Genomic DNA |