A0A891ZJS6 · A0A891ZJS6_9MAGN
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- GeneaccD
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids561 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- acetyl-CoA + N6-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N6-biotinyl-L-lysyl-[protein]
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Cellular Component | chloroplast stroma | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Ranunculales > Ranunculaceae > Thalictroideae > Semiaquilegia
Accessions
- Primary accessionA0A891ZJS6
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-21 | |||||
Sequence: MITHGMAIYLFQILVFSFKQG | ||||||
Chain | PRO_5032942691 | 22-561 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic | |||
Sequence: EVSMERRRFNWMLSKEELEHGRGLSKSIEGIGPIGIGNTNGVDSDSSNNVDHLFGVSDIRNLISDVLVRDNSNGENYSIYFDIENMIFEIEDDRSFLNELKSFFSSYLNDGSKSDNHYYDRYMYDTQSSWNNHITSCITNYLRSEIHIDSYFYSSICIYSSICNESVNSIGSDFDMTNGSDDDRDDLDMTNGSDDGRDDLDMTNGSDFDMTNGSDFDITNGSDDGRDDLDDRDDLDMTNGSDFDITNGSDFDITNGSDNDMTNGSPFYKRFWVLCEDCNELNYKRFLRLKLNVCEHCEFHLKMNSSERIELLMDPGTWDAMDEGLASVDPIEFHSEEDPYKDRIESYQKNTGLTEAVQTGVGQLNGISIAIGIMDFQFMGGSMGSVVGEKITRLIEYATNRSLPLIIVCASGGARMQEGSLSLMQMAKISSASYNYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKEVPEGSQEAEYLFDKGLFDPIVPRNPLKGVLGELFQLHGFFPLNQNSIEIK |
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and two subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 196-262 | Disordered | ||||
Sequence: DMTNGSDDDRDDLDMTNGSDDGRDDLDMTNGSDFDMTNGSDFDITNGSDDGRDDLDDRDDLDMTNGS | ||||||
Compositional bias | 204-225 | Basic and acidic residues | ||||
Sequence: DRDDLDMTNGSDDGRDDLDMTN | ||||||
Compositional bias | 226-240 | Polar residues | ||||
Sequence: GSDFDMTNGSDFDIT | ||||||
Compositional bias | 241-260 | Basic and acidic residues | ||||
Sequence: NGSDDGRDDLDDRDDLDMTN | ||||||
Domain | 292-561 | CoA carboxyltransferase N-terminal | ||||
Sequence: FWVLCEDCNELNYKRFLRLKLNVCEHCEFHLKMNSSERIELLMDPGTWDAMDEGLASVDPIEFHSEEDPYKDRIESYQKNTGLTEAVQTGVGQLNGISIAIGIMDFQFMGGSMGSVVGEKITRLIEYATNRSLPLIIVCASGGARMQEGSLSLMQMAKISSASYNYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKEVPEGSQEAEYLFDKGLFDPIVPRNPLKGVLGELFQLHGFFPLNQNSIEIK | ||||||
Zinc finger | 296-318 | C4-type | ||||
Sequence: CEDCNELNYKRFLRLKLNVCEHC |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length561
- Mass (Da)62,978
- Last updated2021-09-29 v1
- ChecksumAEE9079CCB6D77F6
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 204-225 | Basic and acidic residues | ||||
Sequence: DRDDLDMTNGSDDGRDDLDMTN | ||||||
Compositional bias | 226-240 | Polar residues | ||||
Sequence: GSDFDMTNGSDFDIT | ||||||
Compositional bias | 241-260 | Basic and acidic residues | ||||
Sequence: NGSDDGRDDLDDRDDLDMTN |