A0A853MFH2 · A0A853MFH2_9CYAN
- ProteinPhosphoadenosine 5'-phosphosulfate reductase
- GenecysH
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids234 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
Catalytic activity
- [thioredoxin]-disulfide + sulfite + adenosine 3',5'-bisphosphate + 2 H+ = [thioredoxin]-dithiol + 3'-phosphoadenylyl sulfate
RHEA-COMP:10700 CHEBI:50058 Position: n/n+3+ CHEBI:17359 + CHEBI:58343 + 2 CHEBI:15378 = RHEA-COMP:10698 CHEBI:29950 Position: nCHEBI:29950 Position: n+3+ CHEBI:58339
Pathway
Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 230 | Nucleophile; cysteine thiosulfonate intermediate | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | phosphoadenylyl-sulfate reductase (thioredoxin) activity | |
Biological Process | hydrogen sulfide biosynthetic process | |
Biological Process | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoadenosine 5'-phosphosulfate reductase
- EC number
- Short namesPAPS reductase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Aphanizomenonaceae > Cylindrospermopsis
Accessions
- Primary accessionA0A853MFH2
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 36-208 | Phosphoadenosine phosphosulphate reductase | ||||
Sequence: LVQTSAFNVDDLIITHILYEVLDHPTPVIFLDTLHHFEQTLDLVAKAKTVYGLDLKTYKVPNVYSREEFAAKYGEALWDTDISKFHQVTKIEPLQRGLDELNTVAWITGRRRDQAVTRANMPVFELDNQGRLKINPLATWTRKESWEYVAEYKVIYNPLHDQGYPSIGDEPIT |
Sequence similarities
Belongs to the PAPS reductase family. CysH subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length234
- Mass (Da)26,652
- Last updated2021-09-29 v1
- ChecksumF0B877937DD8902B