A0A852MZB7 · A0A852MZB7_9PASS
- ProteinAMD monooxygenase
- GenePam
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids984 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- a [peptide]-C-terminal (2S)-2-hydroxyglycine = a [peptide]-C-terminal amide + glyoxylate
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 Cu2+ ions per subunit.
Note: Binds one Zn2+ ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 103 | Cu2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 104 | Cu2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 168 | Cu2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 238 | Cu2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 240 | Cu2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 310 | Cu2+ 1 (UniProtKB | ChEBI); catalytic | |||
Binding site | 514 | Ca2+ (UniProtKB | ChEBI); structural | |||
Binding site | 527 | C-terminal Xaa-(2S)-2-hydroxyglycine residue (UniProtKB | ChEBI) of a protein (UniProtKB | ChEBI) | |||
Binding site | 579 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 581 | Ca2+ (UniProtKB | ChEBI); structural | |||
Binding site | 647 | C-terminal Xaa-(2S)-2-hydroxyglycine residue (UniProtKB | ChEBI) of a protein (UniProtKB | ChEBI) | |||
Binding site | 683 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 699 | C-terminal Xaa-(2S)-2-hydroxyglycine residue (UniProtKB | ChEBI) of a protein (UniProtKB | ChEBI) | |||
Binding site | 780 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 781 | Ca2+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Cellular Component | transport vesicle membrane | |
Molecular Function | copper ion binding | |
Molecular Function | lyase activity | |
Molecular Function | peptidylglycine monooxygenase activity | |
Biological Process | peptide metabolic process |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Submitted names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Sylvioidea > Timaliidae > Pteruthius
Accessions
- Primary accessionA0A852MZB7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 860-884 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond, glycosylation.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-21 | ||||
Chain | PRO_5032767664 | 22-984 | |||
Disulfide bond | 43↔182 | ||||
Disulfide bond | 77↔122 | ||||
Disulfide bond | 110↔127 | ||||
Disulfide bond | 223↔330 | ||||
Disulfide bond | 289↔311 | ||||
Disulfide bond | 627↔648 | ||||
Disulfide bond | 695↔706 | ||||
Glycosylation | 759 | N-linked (GlcNAc...) asparagine | |||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, repeat, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 61-172 | Copper type II ascorbate-dependent monooxygenase N-terminal | |||
Domain | 197-342 | Copper type II ascorbate-dependent monooxygenase C-terminal | |||
Repeat | 567-605 | NHL | |||
Repeat | 613-658 | NHL | |||
Repeat | 676-710 | NHL | |||
Region | 948-984 | Disordered | |||
Sequence similarities
In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length984
- Mass (Da)110,184
- Last updated2021-09-29 v1
- MD5 ChecksumFFFD351D999BC50A3791870F12ACFB0B
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Non-terminal residue | 984 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WEIY01000300 EMBL· GenBank· DDBJ | NXY06128.1 EMBL· GenBank· DDBJ | Genomic DNA |