A0A852MM56 · A0A852MM56_9PASS
- ProteinAminopeptidase
- GeneEnpep
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids940 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 215 | substrate | |||
Binding site | 349-353 | substrate | |||
Binding site | 385 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 386 | Proton acceptor | |||
Binding site | 389 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 408 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Site | 471 | Transition state stabilizer | |||
Binding site | 875 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | plasma membrane | |
Molecular Function | metalloaminopeptidase activity | |
Molecular Function | peptide binding | |
Molecular Function | zinc ion binding | |
Biological Process | peptide catabolic process | |
Biological Process | proteolysis | |
Biological Process | regulation of blood pressure |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAminopeptidase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Neoaves > Telluraves > Australaves > Passeriformes > Sylvioidea > Timaliidae > Pteruthius
Accessions
- Primary accessionA0A852MM56
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass type II membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 18-38 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Homodimer; disulfide-linked.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 38-65 | Disordered | |||
Compositional bias | 45-61 | Polar residues | |||
Domain | 90-278 | Aminopeptidase N-like N-terminal | |||
Domain | 313-530 | Peptidase M1 membrane alanine aminopeptidase | |||
Domain | 605-921 | ERAP1-like C-terminal | |||
Sequence similarities
Belongs to the peptidase M1 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length940
- Mass (Da)108,044
- Last updated2021-09-29 v1
- MD5 Checksum9C99B75E9834A091CDC7CBE6922E6645
Features
Showing features for non-terminal residue, compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Non-terminal residue | 1 | ||||
Compositional bias | 45-61 | Polar residues | |||
Non-terminal residue | 940 | ||||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WEIY01000252 EMBL· GenBank· DDBJ | NXY05370.1 EMBL· GenBank· DDBJ | Genomic DNA |