A0A851G0K9 · A0A851G0K9_9ENTR
- ProteinGlutathione hydrolase proenzyme
- Geneggt
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids581 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate
Pathway
Sulfur metabolism; glutathione metabolism.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 115 | L-glutamate (UniProtKB | ChEBI) | |||
Active site | 392 | Nucleophile | |||
Binding site | 410-412 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 434 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 463-464 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 485 | L-glutamate (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | acyltransferase activity | |
Molecular Function | glutathione hydrolase activity | |
Biological Process | glutathione biosynthetic process | |
Biological Process | glutathione catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutathione hydrolase proenzyme
- EC number
- Cleaved into 2 chains
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Enterobacter
Accessions
- Primary accessionA0A851G0K9
Proteomes
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-24 | ||||
Chain | PRO_5032511956 | 25-581 | Glutathione hydrolase proenzyme | ||
Post-translational modification
Cleaved by autocatalysis into a large and a small subunit.
Keywords
- PTM
Interaction
Subunit
This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.
Structure
Sequence
- Sequence statusComplete
- Length581
- Mass (Da)61,814
- Last updated2021-09-29 v1
- ChecksumC499BED111C9DBDE
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACASJ010000001 EMBL· GenBank· DDBJ | NWJ78092.1 EMBL· GenBank· DDBJ | Genomic DNA |