A0A847UCD7 · A0A847UCD7_HALAR

  • Protein
    6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating
  • Gene
    gnd
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NAD to NADH.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site7-12NAD+ (UniProtKB | ChEBI)
Binding site67-69NAD+ (UniProtKB | ChEBI)
Binding site95NAD+ (UniProtKB | ChEBI)
Binding site95substrate
Binding site118substrate
Binding site118-120substrate
Active site169Proton acceptor
Binding site172-173substrate
Active site176Proton donor
Binding site177substrate
Binding site268substrate

GO annotations

AspectTerm
Molecular FunctionNAD+ binding
Molecular FunctionNADP binding
Molecular Functionphosphogluconate dehydrogenase (decarboxylating) activity
Biological ProcessD-gluconate metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating
  • EC number
  • Short names
    6PGDH

Gene names

    • Name
      gnd
    • ORF names
      GOC77_09310

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Pws5
  • Taxonomic lineage
    Archaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloarculaceae > Haloarcula

Accessions

  • Primary accession
    A0A847UCD7

Proteomes

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain165-2966-phosphogluconate dehydrogenase C-terminal

Sequence similarities

Belongs to the 6-phosphogluconate dehydrogenase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    299
  • Mass (Da)
    32,227
  • Last updated
    2021-09-29 v1
  • Checksum
    D53346DC0A399616
MELGVIGLGRMGRIVVDRVLEAGHEAVVFDIDEESVADAADAGARPASSIVDLAEKLGSEKRIWLMVPAGDPVDAALDELAPVLDSDDIVVDGGNSYFEDSVRRAESTDAAYLDCGTSGGPAGAELGFSLMVGGPQWAYDELVPVFDAVATGPDGHDRMGPAGSGHYVKMVHNGVEYALMQTYGEGFELLANGRYDLDLESVANTWNNGAVIRSWLLELCEEAFREEGNDLGDVADRVEGGSTGTWTVQEALEQEVPVPLIYQSLAERFGSRADDGRFSRRLASRLRYGFGRHDVPRRE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WOWA01000004
EMBL· GenBank· DDBJ
NLV13463.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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