A0A847UCD7 · A0A847UCD7_HALAR
- Protein6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating
- Genegnd
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids299 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NAD to NADH.
Catalytic activity
- 6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH
Pathway
Carbohydrate degradation; pentose phosphate pathway.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7-12 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 67-69 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 95 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 95 | substrate | |||
Binding site | 118 | substrate | |||
Binding site | 118-120 | substrate | |||
Active site | 169 | Proton acceptor | |||
Binding site | 172-173 | substrate | |||
Active site | 176 | Proton donor | |||
Binding site | 177 | substrate | |||
Binding site | 268 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | NAD+ binding | |
Molecular Function | NADP binding | |
Molecular Function | phosphogluconate dehydrogenase (decarboxylating) activity | |
Biological Process | D-gluconate metabolic process | |
Biological Process | pentose-phosphate shunt, oxidative branch |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name6-phosphogluconate dehydrogenase, NAD(+)-dependent, decarboxylating
- EC number
- Short names6PGDH
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Stenosarchaea group > Halobacteria > Halobacteriales > Haloarculaceae > Haloarcula
Accessions
- Primary accessionA0A847UCD7
Proteomes
Interaction
Subunit
Homotetramer.
Structure
Sequence
- Sequence statusComplete
- Length299
- Mass (Da)32,227
- Last updated2021-09-29 v1
- ChecksumD53346DC0A399616
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WOWA01000004 EMBL· GenBank· DDBJ | NLV13463.1 EMBL· GenBank· DDBJ | Genomic DNA |