A0A847LN70 · A0A847LN70_9SPIR

  • Protein
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
  • Gene
    murG
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site14-16UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site178UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site227UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)
Binding site343UDP-N-acetyl-alpha-D-glucosamine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionundecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity
Biological Processcarbohydrate metabolic process
Biological Processcell division
Biological Processcell wall organization
Biological Processlipid glycosylation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
  • EC number
  • Alternative names
    • Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Gene names

    • Name
      murG
    • ORF names
      GX435_01550

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • AS27yjCOA_19
  • Taxonomic lineage
    Bacteria > Spirochaetota > Spirochaetia > Spirochaetales > Exilispira

Accessions

  • Primary accession
    A0A847LN70

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane84-102Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-154Glycosyltransferase family 28 N-terminal
Domain221-378Glycosyl transferase family 28 C-terminal

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    419
  • Mass (Da)
    47,180
  • Last updated
    2021-09-29 v1
  • Checksum
    BF136DBB2D4EAE35
MKKSKKAIVVGGGTGGHIIPAVVVAKALKNKGYSVVWIGSKKSYELEEKLIRFSFPNIKIYHIPSGKLRRSGSTLRTLIDLRNIADIFAFISGIFVSFFILLKEKPLFVFSKGGFVSVPVAISCKMTKVPFFTHESDYTVGLANKINLKFSKKFFYSFEDTLKYLPENKAIFSSNPVREEFFSNNKDEGLKRSDKITNSLPLFDEKVKDFFLDSDLNSKLILILGGSLGSQRINNIIFKLAPILTQKYLIIHQTGKLNDLNLNFNSGKEEKINQGNSNKYFKFNPFGLKGYLQIEFIYNGIAELMKLSDLIISRAGANLVFEIVASKTPAIFIPLKTASRGEQENNARYFAKKGNYIVLDEEKLDDKILFNEIEKIFDSQILIKGSQLDSQVATININSLIKAEDIIISSIEKELKINS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAYUW010000023
EMBL· GenBank· DDBJ
NLJ04379.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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