A0A845KWF7 · A0A845KWF7_9FIRM

  • Protein
    Glutamate--tRNA ligase
  • Gene
    gltX
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site109Zn2+ (UniProtKB | ChEBI)
Binding site111Zn2+ (UniProtKB | ChEBI)
Binding site139Zn2+ (UniProtKB | ChEBI)
Binding site141Zn2+ (UniProtKB | ChEBI)
Binding site259ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionglutamate-tRNA ligase activity
Molecular FunctiontRNA binding
Molecular Functionzinc ion binding
Biological Processglutamyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glutamate--tRNA ligase
  • EC number
  • Alternative names
    • Glutamyl-tRNA synthetase
      (GluRS
      )

Gene names

    • Name
      gltX
    • ORF names
      GT508_08700

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • BIOML-A1
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Lachnospirales > Lachnospiraceae > Dorea

Accessions

  • Primary accession
    A0A845KWF7

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Monomer.

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain3-325Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic
Motif10-20'HIGH' region
Motif256-260'KMSKS' region
Domain339-482Aminoacyl-tRNA synthetase class I anticodon-binding

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    487
  • Mass (Da)
    55,513
  • Last updated
    2021-09-29 v1
  • Checksum
    53A3BA5EF8150E80
MSKVRTRFAPSPTGRMHVGNLRTALYTYLIAKHEDGDFILRIEDTDQERFVEGALDIIYRTLKETGLVHDEGPDKDGGVGPYVQSERNAQGLYLKYAEQLIEQGDAYYCFCDKERLESLKSKVSDEDGGTEIVVYDKHCLHLSKEEIEANLAAGKPHVIRFNMPTEGTTTFHDEIYGDITVPNEELDDLILIKSDGYPTYNFANVVDDHLMGITHVVRGNEYLSSAPKYNKIYEAFGWDVPIYVHCPLITDENHKKLSKRCGHSSYEDLIEQGFVTEAVVNYVALLGWSPEGNQEIFSLEELVKAFDFHRMNKSPAVFDLGKLKWMNGEYIKAMDFDKFYERAEGYIRKVITKDYDLKKIAALVKSRIEIFPDIAEQIDFFEAVPEYDTAMYCHKKMKTNEENSLEVLREVLPLLEAQEDYSNDALFALLKSYVDEKGVKVGYVMWPIRTAVSGKQSTPGGATEIMEILGKEESVKRIKDGIELLSK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WWSA01000019
EMBL· GenBank· DDBJ
MZK44629.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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