A0A841EQY9 · A0A841EQY9_9BACL
- ProteinAspartokinase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids405 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine.
Catalytic activity
- L-aspartate + ATP = 4-phospho-L-aspartate + ADP
Pathway
Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 7-10 | ATP (UniProtKB | ChEBI) | |||
Binding site | 52 | substrate | |||
Binding site | 79 | substrate | |||
Binding site | 178-179 | ATP (UniProtKB | ChEBI) | |||
Binding site | 189 | ATP (UniProtKB | ChEBI) | |||
Binding site | 214-215 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | aspartate kinase activity | |
Molecular Function | ATP binding | |
Biological Process | diaminopimelate biosynthetic process | |
Biological Process | homoserine biosynthetic process | |
Biological Process | lysine biosynthetic process via diaminopimelate | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAspartokinase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillati > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus
Accessions
- Primary accessionA0A841EQY9
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length405
- Mass (Da)43,551
- Last updated2021-09-29 v1
- MD5 Checksum8E1576D39875E5CC90237AFBCA16A38E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JACHKG010000001 EMBL· GenBank· DDBJ | MBB6019402.1 EMBL· GenBank· DDBJ | Genomic DNA |