A0A835JBA2 · A0A835JBA2_9ROSI
- Protein3-hydroxyisobutyrate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1398 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+
Pathway
Amino-acid degradation; L-valine degradation.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | 3-hydroxyisobutyrate dehydrogenase activity | |
Molecular Function | ATP binding | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Molecular Function | protein kinase activity | |
Biological Process | protein phosphorylation | |
Biological Process | valine catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-hydroxyisobutyrate dehydrogenase
- EC number
- Short namesHIBADH
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Malpighiales > Salicaceae > Saliceae > Salix
Accessions
- Primary accessionA0A835JBA2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 636-659 | Helical | ||||
Sequence: VVVIVACVIALLILIMLAIFILYI |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-18 | |||||
Sequence: MNLLRLLLLSLFFLSAMG | ||||||
Chain | PRO_5032803278 | 19-1398 | 3-hydroxyisobutyrate dehydrogenase | |||
Sequence: QLPSQDILALLEFKKGIKHDPTGYVLESWNEESIDFNGCPSSWNGIVCNGENVAGVVLDNLGLSADVDLSVFANLTLLVKLSMANNSITGKIPDNVGDFKSLQFMDVSNNLFSSSLPPGIGKLGRLRNLSLAGNNFSGSLPDSISGFVSIQSLDLSRNSFSGPLPVSLARLNNLVYLNLSSNEFTKRIPKGFELISSLQVFDLHGNMFDGHLDGLFFLETNASHVDISGNMLVSSSSQRLLPGMSGSIKLLNLSHNQLSGSLLNGGDVQLFASVKVLDLSYNRLSGELPGFDFAYELQVLRLSNNRFSGSVPNDLLKGDSLLLNELDLSANNLSGPISMIMSTTLRVLDLSSNVLGGELPLVTGSCAVLHLSNNRFEGNLTRMVKWGDIEYLDLSQNHLTGPIPEIAPQFLRLNYLNLSHNSLTSSLPKAITQYPKLRVLDLSSNQLDGSMSTDLLMSPTLQEIHLENNLLDGAIVFSPPPNSKSNLQVIDLSHNQLDGYFPDRFDSLSGLQVLNLAGNNLSGSLPSSMADMSSLILLDLSENHFTGPLPNNLSENIGSFNVSYNDLSGVVPENLRRFPSSSFYPGNNRLRLPNGPPGPNNLPGGHSGGKPIKTIVKVVVIVACVIALLILIMLAIFILYIRTRSNPPSQVTNTGTRRHRQTNPSGTSGTGKAGALVVSAEDLVASRKGSSSEIISPDEKIAAVTGFSPAKHSHLSWSPGSGDSFAAETLARLDVGSPDRLVGDLYFLDDTITMTPEELSRAPAEVLGRSSHGTSYRATLDSGVFITVKWLREGVAKQRKEFAKEAKKFANIRHPNVVGLRGYYWGPTQHEKLILSDYISPGSLASFLYDRPGRKGPPLTWVQRLKIAVDVARGLNYLHFDRAVPHGNLKATNILLDGPDLNARVADYCLHRLMTQSGTIEQLLDAGVLGYRAPELAASKKPLPSFKSDVYAFGMIMLELLTGRCAGDVISGDGGSVDLTDWVRLRAMECFDPALVPEMVNPAVDKGMKEVLGIALRCIRARASLSLLKTKSPFFQYVPLHGFSSSQFSSQFENQTSGSTGLGDDKQLNEKSVGFIGLGNMGSRMANNLIKNGYKVAVHDINCNVMKMFSDMGVPTKETPFEVAEASDVVITMLPSSSHVLDVYTGPNGVLRCANLMRPQLLIDSSTIDPQTSRKVSVAVSNCILKEKKDHWEKPVMLDAPVSGGVLAAEAGTLTFMVGGSEDAYLAAKPLFLSMGKNAIYCGGAGTGSAAKICNNLAMAVSMLGVSEAFALGQSLGISAGTLTKVINTSSARCWSSDSYNPVPGVMEGVPASRNYTGGFASKLMAKDLNLAATSAEEVGLQCPLTYQAHEIYTELCKDGHESKDFSCVFRHYYSGKDEL |
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 666-690 | Disordered | ||||
Sequence: PSQVTNTGTRRHRQTNPSGTSGTGK | ||||||
Domain | 779-1053 | Protein kinase | ||||
Sequence: RAPAEVLGRSSHGTSYRATLDSGVFITVKWLREGVAKQRKEFAKEAKKFANIRHPNVVGLRGYYWGPTQHEKLILSDYISPGSLASFLYDRPGRKGPPLTWVQRLKIAVDVARGLNYLHFDRAVPHGNLKATNILLDGPDLNARVADYCLHRLMTQSGTIEQLLDAGVLGYRAPELAASKKPLPSFKSDVYAFGMIMLELLTGRCAGDVISGDGGSVDLTDWVRLRAMECFDPALVPEMVNPAVDKGMKEVLGIALRCIRARASLSLLKTKSPFF |
Sequence similarities
Belongs to the HIBADH-related family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,398
- Mass (Da)150,613
- Last updated2021-09-29 v1
- ChecksumB8EE8787C037AF81
Keywords
- Technical term