A0A834NUQ4 · A0A834NUQ4_VESGE
- ProteinATP-binding cassette sub-family B member 6
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids796 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
Catalytic activity
- ATP + H2O + heme b(in) = ADP + H+ + heme b(out) + phosphateThis reaction proceeds in the forward direction.
CHEBI:30616 + CHEBI:15377 + heme b (in)CHEBI:60344= CHEBI:456216 + CHEBI:15378 + heme b (out)CHEBI:60344+ CHEBI:43474 - ATP + H2O + pheophorbide a(in) = ADP + H+ + pheophorbide a(out) + phosphateThis reaction proceeds in the forward direction.
- ATP + H2O + protoporphyrin IX(in) = ADP + H+ + phosphate + protoporphyrin IX(out)This reaction proceeds in the forward direction.
- ATP + H2O + uroporphyrin I(in) = ADP + H+ + phosphate + uroporphyrin I(out)This reaction proceeds in the forward direction.
- ATP + H2O + uroporphyrin III(in) = ADP + H+ + phosphate + uroporphyrin III(out)This reaction proceeds in the forward direction.
- ATP + coproporphyrin I(in) + H2O = ADP + coproporphyrin I(out) + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + coproporphyrin III(in) + H2O = ADP + coproporphyrin III(out) + H+ + phosphateThis reaction proceeds in the forward direction.
- ATP + coproporphyrinogen III(in) + H2O = ADP + coproporphyrinogen III(out) + H+ + phosphateThis reaction proceeds in the forward direction.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | early endosome membrane | |
Cellular Component | extracellular region | |
Cellular Component | Golgi membrane | |
Cellular Component | lysosomal membrane | |
Cellular Component | melanosome membrane | |
Cellular Component | mitochondrial outer membrane | |
Cellular Component | multivesicular body membrane | |
Molecular Function | ABC-type heme transporter activity | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | heme binding |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameATP-binding cassette sub-family B member 6
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Vespoidea > Vespidae > Vespinae > Vespula
Accessions
- Primary accessionA0A834NUQ4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Golgi apparatus membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Mitochondrion outer membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 28-47 | Helical | ||||
Sequence: FFLYLVPLLSVLRIILQAVV | ||||||
Transmembrane | 53-72 | Helical | ||||
Sequence: IYGYMILTTVLTLIIYPYSI | ||||||
Transmembrane | 93-111 | Helical | ||||
Sequence: LVLLGFWTLALVAENLVFI | ||||||
Transmembrane | 131-149 | Helical | ||||
Sequence: MAIFVLRYVSNLMIFAIGL | ||||||
Transmembrane | 212-232 | Helical | ||||
Sequence: VIFCFGLLILGRLINLYVPIY | ||||||
Transmembrane | 252-272 | Helical | ||||
Sequence: ILIYVAFKFLQGGGTGGMGLL | ||||||
Transmembrane | 329-352 | Helical | ||||
Sequence: LLNYILFSIIPTIVDIIVAIVFFI | ||||||
Transmembrane | 358-378 | Helical | ||||
Sequence: WFGLIVFITMSLYITATIMVT | ||||||
Transmembrane | 445-466 | Helical | ||||
Sequence: ILQNVIVCCGLLTGSLLCLHMI | ||||||
Transmembrane | 478-498 | Helical | ||||
Sequence: ILFASYIIQLYVPLNWFGTYY |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 213-503 | ABC transmembrane type-1 | ||||
Sequence: IFCFGLLILGRLINLYVPIYNGKIVDSIRVAPTEFRWDLILIYVAFKFLQGGGTGGMGLLNNLRSFLWIRIQQFTTQEVEVELFKHLHGLSLRWHFGRKTGEVLRVMDRGTDSINNLLNYILFSIIPTIVDIIVAIVFFISTFNKWFGLIVFITMSLYITATIMVTEWRVKFQRRMNLADNVQKARSVDSLLNFETVKYYNAESYEVDCYKKAILDFQIEEWKSMVTLNILNILQNVIVCCGLLTGSLLCLHMIVTDTGLTIGDYILFASYIIQLYVPLNWFGTYYRAIQK | ||||||
Domain | 537-771 | ABC transporter | ||||
Sequence: VEFSNVSFSYTSDRMVLRNISFIAPAGKTIAFVGPSGAGKSTILRLLFRFYDIEEGSILIDGQNVKTVKQSSLRSAIGVVPQDTVLFNNTIKYNIQYGRIDAPEADVIEAAKNADIHDRILTFPNGYETQVGERGLRLSGGEKQRVAIARTILKAPKIILLDEATSSLDTHTERNIQLALYRVCTNRTTIIIAHRLSTVIHADEILVLRNGEIVERGRHEELISYDGVYHAMWQE | ||||||
Compositional bias | 776-791 | Polar residues | ||||
Sequence: DTEVNQGETVPASSET | ||||||
Region | 776-796 | Disordered | ||||
Sequence: DTEVNQGETVPASSETKLEVS |
Sequence similarities
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length796
- Mass (Da)91,104
- Last updated2021-09-29 v1
- Checksum04CFF6B879BCDD09
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 776-791 | Polar residues | ||||
Sequence: DTEVNQGETVPASSET |
Keywords
- Technical term