A0A832SYB5 · A0A832SYB5_9EURY
- Protein5,10-methylenetetrahydromethanopterin reductase
- Genemer
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids331 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Catalyzes the reversible reduction of methylene-H4MPT to methyl-H4MPT.
Catalytic activity
- 5-methyl-5,6,7,8-tetrahydromethanopterin + H+ + oxidized coenzyme F420-(gamma-L-Glu)(n) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)
CHEBI:58116 + CHEBI:15378 + oxidized coenzyme F420-(γ-L-Glu)(n) RHEA-COMP:12939 = CHEBI:57818 + reduced coenzyme F420-(γ-L-Glu)(n) RHEA-COMP:14378
Pathway
One-carbon metabolism; methanogenesis from CO2; methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 1/2.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity | |
Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | |
Biological Process | methanogenesis, from carbon dioxide | |
Biological Process | one-carbon metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name5,10-methylenetetrahydromethanopterin reductase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Euryarchaeota > Methanomada group > Methanococci > Methanococcales > Methanocaldococcaceae > Methanocaldococcus
Accessions
- Primary accessionA0A832SYB5
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 12-303 | Luciferase-like | ||||
Sequence: PIQKLCYYVKLAEDNGFEYCWITDHYNNRNVYMALTAIAMNTNKIKLGPGVTNPYVRSPAITASAIATLDELSGGRAVLGIGPGDKATFDALGIEWVKPVTTLKESIEVIRKLLAGERVSYEGKVVKIAGAALAVKPIQKAVPVYMGAQGPKMLETAGMIADGVLINASNPKDFEAAIPLIKKGAEAAGRSMDEIDVAAYACMSVDKNADKAKQAAVPVVAFIAAGSPPVVLERHGIDMEKVEAIRNALKSGNFPEAFKNVDDTMLEAFSIYGTPEDVVEKCKKLAEMGVTQ |
Sequence similarities
Belongs to the mer family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length331
- Mass (Da)35,353
- Last updated2021-09-29 v1
- Checksum367B5DFD1EB6EBBD
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DUJR01000005 EMBL· GenBank· DDBJ | HII59170.1 EMBL· GenBank· DDBJ | Genomic DNA |