A0A831KEG7 · A0A831KEG7_9BACT
- ProteinDNA 5'-3' helicase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids566 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
- Couples ATP hydrolysis with the unwinding of duplex DNA at the replication fork by translocating in the 5'-3' direction. This creates two antiparallel DNA single strands (ssDNA). The leading ssDNA polymer is the template for DNA polymerase III holoenzyme which synthesizes a continuous strand.
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | DNA helicase activity | |
Molecular Function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | |
Molecular Function | nucleic acid binding | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA 5'-3' helicase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfobacteria > Desulfobacterales > Desulfobacteraceae
Accessions
- Primary accessionA0A831KEG7
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 16-289 | Helicase ATP-binding | ||||
Sequence: VLAGHLGGYEPRPGQQQMAAAVATALGGSDEISFTEPDQAVCLVVEAETGLGKTLAYLVPAVLSGRKVVVSTNTRNLQDQILKHEIPFIRKYIEPQLRALCVKGRQNYLCLYRWHQYRAAGQPALVADQAADRIDGWLKKTTFADRAELTWLPGASPLWRKICCLPHFCLGGDCPDGAACFLNRLRREAAASRLLVVNHHLLFSDLAVRRSGHGEVLPRYEAVIFDEAHHVENVATTFFGFSFSRYQVLDLAADVERSARSGLAGEKQQEVQGA |
Sequence similarities
Belongs to the helicase family. DinG subfamily.
Family and domain databases
Sequence
- Sequence statusFragment
- Length566
- Mass (Da)62,688
- Last updated2021-09-29 v1
- ChecksumD5DE05983211F222
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 566 | |||||
Sequence: D |