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A0A829XAJ9 · A0A829XAJ9_GLUOY

Function

function

Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Membrane lipid metabolism; glycerophospholipid metabolism.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site11-16NAD+ (UniProtKB | ChEBI)
Binding site15NADPH (UniProtKB | ChEBI)
Binding site35NADPH (UniProtKB | ChEBI)
Binding site101NADPH (UniProtKB | ChEBI)
Binding site101sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site101substrate
Binding site129sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site133NAD+ (UniProtKB | ChEBI)
Binding site133NADPH (UniProtKB | ChEBI)
Active site184Proton acceptor
Binding site184sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site237sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site247sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site248NAD+ (UniProtKB | ChEBI)
Binding site248NADPH (UniProtKB | ChEBI)
Binding site248sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site248-249substrate
Binding site249sn-glycerol 3-phosphate (UniProtKB | ChEBI)
Binding site272NADPH (UniProtKB | ChEBI)
Binding site274NADPH (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Molecular FunctionNAD binding
Biological Processcarbohydrate metabolic process
Biological Processglycerol-3-phosphate biosynthetic process
Biological Processglycerol-3-phosphate catabolic process
Biological Processglycerophospholipid metabolic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glycerol-3-phosphate dehydrogenase [NAD(P)+]
  • EC number
  • Alternative names
    • NAD(P)(+)-dependent glycerol-3-phosphate dehydrogenase
    • NAD(P)H-dependent dihydroxyacetone-phosphate reductase

Gene names

    • Name
      gpsA
    • ORF names
      NBRC3293_1963

Organism names

  • Taxonomic identifier
  • Strain
    • NBRC 3293
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodospirillales > Acetobacteraceae > Gluconobacter

Accessions

  • Primary accession
    A0A829XAJ9

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-20
ChainPRO_503253950821-324Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain7-153Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal
Domain173-312Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    324
  • Mass (Da)
    33,248
  • Last updated
    2021-09-29 v1
  • MD5 Checksum
    EFF0CF2E624FBA240DCEC818CE1199E3
MTTRPHIAVIGAGAWGTALACATAATGADVTLWMRNPVPPGTRTLPRLPDITLPDNVTITGDFPRSADVVLLVTPVQTARDVSTRLQTVLDPAVPVVTCCKGLEQATSLLPLDVLAETMPGRPTGVLSGPNFAIEVAKGLPAAATLACTDLALAQKLTALLNTSSFRLYASDDAAGVQLAGAAKNVIAIGAGITIGAGLGENARAALITRAVAEIGRLAEATGGRASTLAGLAGMGDLILTCTGRGSRNYSVGLELGEGRPLADILASRTTVAEGVLTAPAMLTLARQHNVRAPIIETVTRLLNDGVSIEEARHLLLDRPPTRE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BARJ01000010
EMBL· GenBank· DDBJ
GEM17466.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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