A0A829BM46 · A0A829BM46_STRMG
- ProteinUvrABC system protein A
- GeneuvrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids943 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | excinuclease repair complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Molecular Function | excinuclease ABC activity | |
Molecular Function | zinc ion binding | |
Biological Process | nucleotide-excision repair | |
Biological Process | SOS response |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameUvrABC system protein A
- Short namesUvrA protein
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionA0A829BM46
Proteomes
Subcellular Location
Interaction
Subunit
Forms a heterotetramer with UvrB during the search for lesions.
Structure
Family & Domains
Features
Showing features for zinc finger, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Zinc finger | 251-278 | C4-type | ||||
Sequence: CPVCGFTVPELEPRLFSFNAPFGSCPTC | ||||||
Domain | 605-937 | ABC transporter | ||||
Sequence: DRRKGSGRFIEIKGAAENNLQNINVKFPLGKFIAVTGVSGSGKSTLVNSILKKVIAQKLNRNSEKPGKYKSISGIEHIDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGTRYNSETLEVHYKDKNIAEILNMTINDAAEFFAPIPKIARKIRTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGQVIATGTPEQVAEMTESYTGQYLK | ||||||
Zinc finger | 740-766 | C4-type | ||||
Sequence: CEACSGDGIIKIEMHFLPDVYVPCEVC |
Sequence similarities
Belongs to the ABC transporter superfamily. UvrA family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length943
- Mass (Da)104,120
- Last updated2021-09-29 v1
- Checksum5D23DDAD4157A4B4