A0A828QXU0 · A0A828QXU0_CAMUP
- ProteinDelta-aminolevulinic acid dehydratase
- GenehemB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids327 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 2 5-aminolevulinate = porphobilinogen + 2 H2O + H+
Pathway
Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 119 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 121 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 129 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 196 | Schiff-base intermediate with substrate | |||
Binding site | 206 | 5-aminolevulinate 1 (UniProtKB | ChEBI) | |||
Binding site | 218 | 5-aminolevulinate 1 (UniProtKB | ChEBI) | |||
Binding site | 234 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 249 | Schiff-base intermediate with substrate | |||
Binding site | 275 | 5-aminolevulinate 2 (UniProtKB | ChEBI) | |||
Binding site | 314 | 5-aminolevulinate 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | porphobilinogen synthase activity | |
Molecular Function | zinc ion binding | |
Biological Process | protoporphyrinogen IX biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDelta-aminolevulinic acid dehydratase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Campylobacterota > Epsilonproteobacteria > Campylobacterales > Campylobacteraceae > Campylobacter
Accessions
- Primary accessionA0A828QXU0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homooctamer.
Structure
Sequence
- Sequence statusComplete
- Length327
- Mass (Da)36,633
- Last updated2021-09-29 v1
- ChecksumDB93D2A3B409E303
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AEPU01000008 EMBL· GenBank· DDBJ | EFU72493.1 EMBL· GenBank· DDBJ | Genomic DNA |