A0A812TUM1 · A0A812TUM1_9DINO
- Proteinbranched-chain-amino-acid transaminase
- GeneilvE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2731 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Acts on leucine, isoleucine and valine.
Catalytic activity
- L-isoleucine + 2-oxoglutarate = (S)-3-methyl-2-oxopentanoate + L-glutamate
Cofactor
Pathway
Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.
Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.
Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 1356 | Nucleophile | |||
Active site | 1445 | ||||
Active site | 1447 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | membrane | |
Molecular Function | branched-chain-amino-acid transaminase activity | |
Molecular Function | metalloendopeptidase activity | |
Biological Process | base-excision repair | |
Biological Process | CAAX-box protein processing | |
Biological Process | glutamine metabolic process | |
Biological Process | isoleucine biosynthetic process | |
Biological Process | L-leucine biosynthetic process | |
Biological Process | valine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namebranched-chain-amino-acid transaminase
- EC number
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Sar > Alveolata > Dinophyceae > Suessiales > Symbiodiniaceae > Symbiodinium
Accessions
- Primary accessionA0A812TUM1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 335-359 | Helical | |||
Transmembrane | 371-393 | Helical | |||
Transmembrane | 414-442 | Helical | |||
Transmembrane | 462-483 | Helical | |||
Transmembrane | 495-514 | Helical | |||
Transmembrane | 520-538 | Helical | |||
Transmembrane | 879-902 | Helical | |||
Transmembrane | 922-942 | Helical | |||
Transmembrane | 954-976 | Helical | |||
Transmembrane | 988-1009 | Helical | |||
Transmembrane | 1041-1068 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-29 | Disordered | |||
Compositional bias | 13-29 | Polar residues | |||
Region | 788-807 | Disordered | |||
Domain | 1132-1222 | Methyltransferase | |||
Domain | 1293-1449 | Glutamine amidotransferase | |||
Region | 2299-2328 | Disordered | |||
Compositional bias | 2311-2328 | Basic and acidic residues | |||
Sequence similarities
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,731
- Mass (Da)297,401
- Last updated2021-09-29 v1
- MD5 Checksum83EDB3FDD2B478369238F52BD809A2C9
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 13-29 | Polar residues | |||
Compositional bias | 2311-2328 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAJNJA010025808 EMBL· GenBank· DDBJ | CAE7549768.1 EMBL· GenBank· DDBJ | Genomic DNA |