A0A812T9J1 · A0A812T9J1_9DINO
- ProteintRNA (guanine-N(7)-)-methyltransferase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids404 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.
Catalytic activity
- guanosine46 in tRNA + S-adenosyl-L-methionine = N7-methylguanosine46 in tRNA + S-adenosyl-L-homocysteine
Pathway
tRNA modification; N7-methylguanine-tRNA biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 217 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 240-241 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 275-276 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 295 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Active site | 298 | ||||
Binding site | 373-375 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | nucleus | |
Cellular Component | tRNA methyltransferase complex | |
Molecular Function | tRNA (guanine(46)-N7)-methyltransferase activity | |
Molecular Function | tRNA binding |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA (guanine-N(7)-)-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Sar > Alveolata > Dinophyceae > Suessiales > Symbiodiniaceae > Symbiodinium
Accessions
- Primary accessionA0A812T9J1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 310-332 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-18 | ||||
Chain | PRO_5032382592 | 19-404 | tRNA (guanine-N7-)-methyltransferase | ||
Structure
Sequence
- Sequence statusComplete
- Length404
- Mass (Da)45,081
- Last updated2021-09-29 v1
- ChecksumD861959FB07C8234
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAJNDS010002549 EMBL· GenBank· DDBJ | CAE7522995.1 EMBL· GenBank· DDBJ | Genomic DNA |